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Autoren: Reiner, Iris
Tibubos, Ana N.
Werner, Antonia M.
Ernst, Mareike
Brähler, Elmar
Wiltink, Jörg
Michal, Matthias
Schulz, Andreas
Wild, Philipp S.
Münzel, Thomas
Arnold, Natalie
Mahmoudpour, Seyed Hamidreza
Lackner, Karl J.
Pfeiffer, Norbert
Beutel, Manfred E.
Titel: The association of chronic anxiousness with cardiovascular disease and mortality in the community : results from the Gutenberg Health Study
Online-Publikationsdatum: 18-Dez-2020
Sprache des Dokuments: Englisch
Zusammenfassung/Abstract: In a large German community sample of adults, we investigated the association of chronic anxiousness with cardiovascular disease and mortality. Self-reported anxiousness from 11,643 German adults between 40 and 80 years of age from the Gutenberg Health Study (GHS) was analyzed over 5 years. Multivariable regression modeling assessed the relation between the variables, cardiovascular disease and mortality. Twelve percent of the participants reported consistently raised (chronic) anxiousness over at least 2.5 years. Anxiousness was more often reported by female, younger participants with a lower socioeconomic status, smokers and those with a family history of stroke and myocardial infarction. New onset of cardiovascular disease was linked to chronic anxiousness in men and new onset of anxiousness in women. However, chronic anxiousness did not predict all-cause mortality. Our results revealed that anxiousness is highly prevalent in German adults from middle to old age, affecting women in particular. In our study, we found sex-specific associations between new onset of cardiovascular disease and different forms of anxiousness in men and women. We suggest that even subclinical levels of anxiety need to be considered as cardiovascular risk factors. To elucidate potential harm of anxiousness for mental and physical health, we propose sex-specific analyses in further research studies, taking age and the course of anxiousness into account.
DDC-Sachgruppe: 610 Medizin
610 Medical sciences
Veröffentlichende Institution: Johannes Gutenberg-Universität Mainz
Organisationseinheit: FB 04 Medizin
Veröffentlichungsort: Mainz
DOI: http://doi.org/10.25358/openscience-5506
Version: Published version
Publikationstyp: Zeitschriftenaufsatz
Weitere Angaben zur Dokumentart: Scientific article
Nutzungsrechte: CC BY
Informationen zu den Nutzungsrechten: https://creativecommons.org/licenses/by/4.0/
Zeitschrift: Scientific Reports
10
Seitenzahl oder Artikelnummer: 12436
Verlag: Macmillan Publishers Limited, part of Springer Nature
Verlagsort: London
Erscheinungsdatum: 2020
ISSN: 2045-2322
URL der Originalveröffentlichung: https://doi.org/10.1038/s41598-020-69427-8
DOI der Originalveröffentlichung: 10.1038/s41598-020-69427-8
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