Please use this identifier to cite or link to this item:
http://doi.org/10.25358/openscience-4878
Authors: | Geyer, Martin Wild, Johannes Hirschmann, Marc Dimitriadis, Zisis Münzel, Thomas Gori, Tommaso Wenzel, Philip |
Title: | Predictors for target vessel failure after recanalization of chronic total occlusions in patients undergoing surveillance coronary angiography |
Online publication date: | 10-Jun-2020 |
Year of first publication: | 2020 |
Language: | english |
Abstract: | (1) Background: Knowledge about predictors for the long-time patency of recanalized chronic total coronary occlusions (CTOs) is limited. Evidence from invasive follow-up in the absence of acute coronary syndrome (routine surveillance coronary angiography) is scarce. (2) Methods: In a monocentric-retrospective analysis, we obtained baseline as well as periprocedural data of patients undergoing routine invasive follow-up. We defined target vessel failure (TVF) as a combined primary endpoint, consisting of re-occlusion, restenosis, and target vessel revascularization (TVR). (3) Results: We included 93 consecutive patients (15.1% female) from October 2013 to May 2018. After a follow-up period of 206 ± 129 days (median 185 (IQR 127–237)), re-occlusion had occurred in 7.5%, restenosis in 11.8%, and TVR in 5.4%; the cumulative incidence of TVF was 15.1%. Reduced TIMI-flow immediately after recanalization (OR for TVR: 11.0 (95% CI: 2.7–45.5), p = 0.001) as well as female gender (OR for TVR: 11.0 (95% CI: 2.1–58.5), p = 0.005) were found to be predictive for pathological angiographic findings at follow-up. Furthermore, higher blood values of high-sensitive troponin after successful revascularization were associated with all endpoints. Interestingly, neither the J-CTO score nor the presence of symptoms at the follow-up visit could be correlated to adverse angiographic results. (4) Conclusions: In this medium-sized cohort of patients with surveillance coronary angiography, we were able to identify reduced TIMI flow and female gender as the strongest predictors for future TVF. Keywords: chronic total occlusion; target vessel failure; re-occlusion; surveillance coronary angiography |
DDC: | 610 Medizin 610 Medical sciences |
Institution: | Johannes Gutenberg-Universität Mainz |
Department: | FB 04 Medizin |
Place: | Mainz |
ROR: | https://ror.org/023b0x485 |
DOI: | http://doi.org/10.25358/openscience-4878 |
URN: | urn:nbn:de:hebis:77-publ-598675 |
Version: | Published version |
Publication type: | Zeitschriftenaufsatz |
License: | CC BY |
Information on rights of use: | https://creativecommons.org/licenses/by/4.0/ |
Journal: | Journal of Clinical Medicine 9 1 |
Pages or article number: | Art. 178 |
Publisher: | MDPI |
Publisher place: | Basel |
Issue date: | 2020 |
ISSN: | 2077-0383 |
Publisher URL: | http://dx.doi.org/10.3390/jcm9010178 |
Publisher DOI: | 10.3390/jcm9010178 |
Appears in collections: | JGU-Publikationen |