Please use this identifier to cite or link to this item:
http://doi.org/10.25358/openscience-2840
Authors: | Thomi, Laura |
Title: | Functional nanocarriers as compartments for artificial cells |
Online publication date: | 27-Jan-2018 |
Year of first publication: | 2018 |
Language: | english |
Abstract: | This work presents an exploratory study towards a functional compartment usable for bottom up approach of a minimal cell. Two projects deal with permeable nanocontainers, either redoxresponsive nanocapsules or permeable polymersomes. The two remaining projects deal with functional nanocontainers, i.e. polymersomes with different surface functionalisations and polymersomes from biodegradable poly(phosphoesters). In conclusion, different nanocarriers bearing either chemical functionalities or responsiveness were developed. In synthetic biology, such containers are needed to separate and protect their cargo and mimic certain cell functions. The functionality introduces a communication path to the outside, e.g. through redox-responsiveness or adhesion. Functional nanocarriers serve as a platform to develop interacting systems of increasing complexity until at some point, those complex systems resemble a minimal cell. |
DDC: | 540 Chemie 540 Chemistry and allied sciences |
Institution: | Johannes Gutenberg-Universität Mainz |
Department: | FB 09 Chemie, Pharmazie u. Geowissensch. |
Place: | Mainz |
ROR: | https://ror.org/023b0x485 |
DOI: | http://doi.org/10.25358/openscience-2840 |
URN: | urn:nbn:de:hebis:77-diss-1000018627 |
Version: | Original work |
Publication type: | Dissertation |
License: | In Copyright |
Information on rights of use: | https://rightsstatements.org/vocab/InC/1.0/ |
Extent: | 133 Seiten |
Appears in collections: | JGU-Publikationen |
Files in This Item:
File | Description | Size | Format | ||
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100001862.pdf | 6.81 MB | Adobe PDF | View/Open |