Please use this identifier to cite or link to this item: http://doi.org/10.25358/openscience-259
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dc.contributor.authorGonzalez-Escamilla, Gabriel-
dc.contributor.authorMuthuraman, Muthuraman-
dc.contributor.authorChirumamilla, Venkata C.-
dc.contributor.authorVogt, Johannes-
dc.contributor.authorGroppa, Sergiu-
dc.date.accessioned2018-12-19T13:35:20Z-
dc.date.available2018-12-19T14:35:20Z-
dc.date.issued2018-
dc.identifier.urihttps://openscience.ub.uni-mainz.de/handle/20.500.12030/261-
dc.description.abstractMaturation and aging are important life periods that are linked to drastic brain reorganization processes which are essential for mental health. However, the development of generalized theories for delimiting physiological and pathological brain remodeling through life periods linked to healthy states and resilience on one side or mental dysfunction on the other remains a challenge. Furthermore, important processes of preservation and compensation of brain function occur continuously in the cerebral brain networks and drive physiological responses to life events. Here, we review research on brain reorganization processes across the lifespan, demonstrating brain circuits remodeling at the structural and functional level that support mental health and are parallelized by physiological trajectories during maturation and healthy aging. We show evidence that aberrations leading to mental disorders result from the specific alterations of cerebral networks and their pathological dynamics leading to distinct excitability patterns. We discuss how these series of large-scale responses of brain circuits can be viewed as protective or malfunctioning mechanisms for the maintenance of mental health and resilience.en_GB
dc.description.sponsorshipDFG, Open Access-Publizieren Universität Mainz / Universitätsmedizin-
dc.language.isoeng-
dc.rightsCC BYde_DE
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/-
dc.subject.ddc610 Medizinde_DE
dc.subject.ddc610 Medical sciencesen_GB
dc.titleBrain networks reorganization during maturation and healthy aging-emphases for resilienceen_GB
dc.typeZeitschriftenaufsatzde_DE
dc.identifier.urnurn:nbn:de:hebis:77-publ-587159-
dc.identifier.doihttp://doi.org/10.25358/openscience-259-
jgu.type.dinitypearticle-
jgu.type.versionPublished versionen_GB
jgu.type.resourceText-
jgu.organisation.departmentFB 04 Medizin-
jgu.organisation.number2700-
jgu.organisation.nameJohannes Gutenberg-Universität Mainz-
jgu.rights.accessrightsopenAccess-
jgu.journal.titleFrontiers in psychiatry-
jgu.journal.volume9-
jgu.pages.alternativeArt. 601-
jgu.publisher.year2018-
jgu.publisher.nameFrontiers Research Foundation-
jgu.publisher.placeLausanne-
jgu.publisher.urihttp://dx.doi.org/10.3389/fpsyt.2018.00601-
jgu.publisher.issn1664-0640-
jgu.organisation.placeMainz-
jgu.subject.ddccode610-
opus.date.accessioned2018-12-19T13:35:20Z-
opus.date.modified2019-01-16T09:10:07Z-
opus.date.available2018-12-19T14:35:20-
opus.subject.dfgcode00-000-
opus.organisation.stringFB 04: Medizin: Neurochirurgische Klinik und Poliklinikde_DE
opus.organisation.stringFB 04: Medizin: Institut für Mikroskopische Anatomie und Neurobiologiede_DE
opus.identifier.opusid58715-
opus.institute.number0441-
opus.institute.number0459-
opus.metadataonlyfalse-
opus.type.contenttypeKeinede_DE
opus.type.contenttypeNoneen_GB
opus.affiliatedMuthuraman, Muthuraman-
opus.affiliatedVogt, Johannes-
opus.affiliatedGroppa, Sergiu-
jgu.publisher.doi10.3389/fpsyt.2018.00601
jgu.organisation.rorhttps://ror.org/023b0x485
Appears in collections:JGU-Publikationen

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