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http://doi.org/10.25358/openscience-20
Autoren: | Beck, Olaf Muensterer, Oliver J. Hofmann, Sarah Rossmann, Heidi Poplawski, Alicia Faber, Jörg Gödeke, Jan |
Titel: | Central venous access devices (CVAD) in pediatric oncology patients : a single-center retrospective study over more than 9 years |
Online-Publikationsdatum: | 24-Jan-2020 |
Erscheinungsdatum: | 2019 |
Sprache des Dokuments: | Englisch |
Zusammenfassung/Abstract: | Central venous access devices (CVAD) provide important benefits in the management of oncological pediatric patients. However, these catheters are responsible for severe complications. Methods: In this context, we aimed to analyze all patients receiving a CVAD in the Department of Pediatric Hematology and Oncology of the University hospital of Mainz over a period of 9 years, focused on CVAD related complications. Data on demographics, as well as intraoperative and postoperative complications were extracted. Results: A total of 296 patients with a mean age 93.2 ± 62.4 months were analyzed. The majority suffered from leukemia (n = 91, 30.7%), lymphomas (n = 50, 16.9%), and brain tumors (n = 48, 16.2%). In 63 (21.3) patients, complications were observed. No death caused by complications of CVADs was found in our series. Catheter-related blood stream infections (BSI) (7.4%) were most prevalent, followed by dislodgements (5.4%), occlusions (2.7%), thrombosis (2.4%), and catheter leakage (2.4%). Insertion site infections were observed in three patients (1.0%). Fifty-nine percent of all patients with catheter-related BSI suffered from Leukemia. In patients with Catheter-related BSIs we detected the condition leukemia as the underlying disease as a risk factor compared to solid tumors as the underlying disease. Overall, totally implanted devices (ports) have a lower complication rate than tunneled catheter. Conclusion: Implantation of CVADs seems to be safe and reliable in this large pediatric patient cohort. Even if complications occur in the long-term management of CVADs, they can be treated successfully and long-term catheter survival rates are excellent. |
DDC-Sachgruppe: | 610 Medizin 610 Medical sciences |
Veröffentlichende Institution: | Johannes Gutenberg-Universität Mainz |
Organisationseinheit: | FB 04 Medizin |
Veröffentlichungsort: | Mainz |
ROR: | https://ror.org/023b0x485 |
DOI: | http://doi.org/10.25358/openscience-20 |
URN: | urn:nbn:de:hebis:77-publ-595199 |
Version: | Published version |
Publikationstyp: | Zeitschriftenaufsatz |
Nutzungsrechte: | CC BY |
Informationen zu den Nutzungsrechten: | https://creativecommons.org/licenses/by/4.0/ |
Zeitschrift: | Frontiers in Pediatrics 7 |
Seitenzahl oder Artikelnummer: | Art. 260 |
Verlag: | Frontiers Media |
Verlagsort: | Lausanne |
Erscheinungsdatum: | 2019 |
ISSN: | 2296-2360 |
URL der Originalveröffentlichung: | http://dx.doi.org/10.3389/fped.2019.00260 |
DOI der Originalveröffentlichung: | 10.3389/fped.2019.00260 |
Enthalten in den Sammlungen: | JGU-Publikationen |
Dateien zu dieser Ressource:
Datei | Beschreibung | Größe | Format | ||
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59519.pdf | 1.52 MB | Adobe PDF | Öffnen/Anzeigen |