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PreviewIssue dateOnline publication dateTitleAuthor(s)
saeed_mohamed_e._m.-drug_repurposi-20210510114527807.pdf.jpg202110-May-2021Drug repurposing using transcriptome sequencing and virtual drug screening in a patient with glioblastomaSaeed, Mohamed E. M.; Kadioglu, Onat; Greten, Henry Johannes; Yildirim, Adem; Mayr, Katharina; Wenz, Frederik; Giordano, Frank; Efferth, Thomas
barthels_fabian-banδit__b’-fac-20210628203840983.pdf.jpg202129-Jun-2021BANΔIT: B’-factor analysis for drug design and structural biologyBarthels, Fabian; Schirmeister, Tanja; Kersten, Christian
selection_of_safe_artemisinin-20220624130755185.pdf.jpg202127-Jun-2022Selection of safe artemisinin derivatives using a machine learning-based cardiotoxicity platform and in vitro and in vivo validationKadioglu, Onat; Klauck, Sabine M.; Fleischer, Edmond; Shan, Letian; Efferth, Thomas
autonomous_dna_nanostructures-20220701085546809.pdf.jpg20211-Jul-2022Autonomous DNA nanostructures instructed by hierarchically concatenated chemical reaction networksDeng, Jie; Walther, Andreas
welker_armin-structure-acti-20210621155711267.pdf.jpg202128-Jun-2021Structure-activity relationships of benzamides and isoindolines designed as SARS-CoV protease inhibitors effective against SARS-CoV-2Welker, Armin; Kersten, Christian; Müller, Christin; Madhugiri, Ramakanth; Zimmer, Collin; Müller, Patrick; Zimmermann, Robert; Hammerschmidt, Stefan; Maus, Hannah; Ziebuhr, John; Sotriffer, Christoph; Schirmeister, Tanja
cymer_florian-small_residues-20211115121527126.pdf.jpg202115-Nov-2021Small residues inhibit homo-dimerization of the human carbonic anhydrase XII transmembrane domainCymer, Florian; Schneider, Dirk
network_pharmacology_of_tript-20220729131545075.pdf.jpg20213-Aug-2022Network pharmacology of triptolide in cancer cells : implications for transcription factor bindingSeo, Ean-Jeong; Dawood, Mona; Hult, Annika K.; Olsson, Martin L.; Efferth, Thomas
2sulfonylpyrimidines_as_privi-20230302115838017.pdf.jpg20212-Mar-20232-sulfonylpyrimidines as privileged warheads for the development of S. aureus sortase A inhibitorsBarthels, Fabian; Meyr, Jessica; Hammerschmidt, Stefan J.; Marciniak, Tessa; Räder, Hans-Joachim; Ziebuhr, Wilma; Engels, Bernd; Schirmeister, Tanja
the_immunosuppressive_activit-20221017113132463.pdf.jpg20219-Nov-2022The immunosuppressive activity of artemisinin-type drugs towards inflammatory and autoimmune diseasesEfferth, Thomas; Oesch, Franz
general_principles_for_the_de-20221017112218212.pdf.jpg20218-Nov-2022General principles for the detection of modified nucleotides in RNA by specific reagentsHelm, Mark; Schmidt-Dengler, Martina C.; Weber, Marlies; Motorin, Yuri