Authors:	Barthelmann, Sara Butsch, Florian Lang, Berenice M. Stege, Henner Großmann, Bernd Schepler, Hadrian Grabbe, Stephan
Title:	Seborrheic keratosis
Online publication date:	11-Mar-2024
Year of first publication:	2023
Language:	english
Abstract:	Seborrheic keratosis (SK) is the most common benign epidermal tumor in clinical dermatological practice. This review summarizes current knowledge about the clinical and histological appearance, epidemiology, pathogenesis, and treatment of SK. There are different subtypes of SK based on clinical presentation and histologic findings. Several factors, including age, genetic predisposition, and possibly also exposure to ultraviolet radiation, are thought to contribute to the development of SK. The lesions can occur on all areas of the body except for the palms and soles, but the most common sites are the face and upper trunk. The diagnosis is usually made clinically, and in some cases by dermatoscopy or histology. Many patients prefer to have the lesions removed for cosmetic reasons although there is no medical indication. Treatment options include surgical therapy, laser therapy, electrocautery, cryotherapy, and topical drug therapy, which is currently in development. Treatment should be individualized depending on the clinical picture and patient preference.
DDC:	610 Medizin 610 Medical sciences
Institution:	Johannes Gutenberg-Universität Mainz
Department:	FB 04 Medizin
Place:	Mainz
ROR:	https://ror.org/023b0x485
DOI:	http://doi.org/10.25358/openscience-10173
Version:	Published version
Publication type:	Zeitschriftenaufsatz
Document type specification:	Other
License:	CC BY-NC-ND
Information on rights of use:	https://creativecommons.org/licenses/by-nc-nd/4.0/
Journal:	JDDG : Journal der Deutschen Dermatologischen Gesellschaft 21 3
Pages or article number:	265 277
Publisher:	Wiley
Publisher place:	Berlin
Issue date:	2023
ISSN:	1610-0387
Publisher DOI:	10.1111/ddg.14984
Appears in collections:	DFG-491381577-H