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PreviewIssue dateOnline publication dateTitleAuthor(s)
düppre_eva-the_j‐_and_g/f-20210108101701006.pdf.jpg20208-Jan-2021The J‐ and G/F‐domains of the major Synechocystis DnaJ protein Sll0897 are sufficient for cell viability but not for heat resistanceDüppre, Eva; Schneider, Dirk
prediction_of_cancer_drug_res-20220913190849926.pdf.jpg201514-Sep-2022Prediction of cancer drug resistance and implications for personalized medicineVolm, Manfred; Efferth, Thomas
identification_of_plakortide_-20220510090302657.pdf.jpg201410-May-2022Identification of plakortide E from the Caribbean sponge Plakortis halichondroides as a trypanocidal protease inhibitor using bioactivity-guided fractionationOli, Swarna; Abdelmohsen, Usama Ramadan; Hentschel, Ute; Schirmeister, Tanja
novel_dengue_virus_ns2bns3_pr-20220913202020725.pdf.jpg20157-Dec-2022Novel dengue virus NS2B/NS3 protease inhibitorsWu, Hongmei; Bock, Stefanie; Snitko, Mariya; Berger, Thilo; Weidner, Thomas; Holloway, Steven; Kanitz, Manuel; Diederich, Wibke E.; Steuber, Holger; Walter, Christof; Hofmann, Daniela; Weißbrich, Benedikt; Spannaus, Ralf; Acosta, Eliana G.; Bartenschlager, Ralf; Engels, Bernd; Schirmeister, Tanja; Bodem, Jochen
nonsecreted_clusterin_isoform-20220712210353740.pdf.jpg201314-Jul-2022Non-secreted clusterin isoforms are translated in rare amounts from distinct human mRNA variants and do not affect bax-mediated apoptosis or the NF-kappaB signaling pathwayProchnow, Hans; Gollan, Rene; Rohne, Philipp; Hassemer, Matthias; Koch-Brandt, Claudia; Baiersdörfer, Markus
selection_of_safe_artemisinin-20220624130755185.pdf.jpg202127-Jun-2022Selection of safe artemisinin derivatives using a machine learning-based cardiotoxicity platform and in vitro and in vivo validationKadioglu, Onat; Klauck, Sabine M.; Fleischer, Edmond; Shan, Letian; Efferth, Thomas
pyrrolizidine_alkaloids_cause-20220701131337232.pdf.jpg20224-Jul-2022Pyrrolizidine alkaloids cause cell cycle and DNA damage repair defects as analyzed by transcriptomics in cytochrome P450 3A4-overexpressing HepG2 clone 9 cellsAbdelfatah, Sara; Naß, Janine; Knorz, Caroline; Klauck, Sabine M.; Küpper, Jan-Heiner; Efferth, Thomas
autonomous_dna_nanostructures-20220701085546809.pdf.jpg20211-Jul-2022Autonomous DNA nanostructures instructed by hierarchically concatenated chemical reaction networksDeng, Jie; Walther, Andreas
synergistic_inhibition_of_ang-20221005103458805.pdf.jpg20135-Oct-2022Synergistic inhibition of angiogenesis by artesunate and captopril in vitro and in vivoKrusche, Benjamin; Arend, Joachim; Efferth, Thomas
cytotoxicity_of_endoperoxides-20220925182710959.pdf.jpg201721-Oct-2022Cytotoxicity of endoperoxides from the Caribbean sponge Plakortis halichondrioides towards sensitive and multidrug-resistant leukemia cells : acids vs. esters activity evaluationSchirmeister, Tanja; Oli, Swarna; Wu, Hongmei; Della Sala, Gerardo; Costantino, Valeria; Seo, Ean-Jeong; Efferth, Thomas