Deep learning-enhanced ultra-high-resolution CT imaging for superior temporal bone visualization

dc.contributor.authorBrockstedt, Lavinia
dc.contributor.authorGrauhan, Nils F.
dc.contributor.authorKronfeld, Andrea
dc.contributor.authorAbello Mercado, Mario Alberto
dc.contributor.authorDöge, Julia
dc.contributor.authorSanner, Antoine
dc.contributor.authorBrockmann, Marc A.
dc.contributor.authorOthman, Ahmed E.
dc.date.accessioned2026-07-17T08:11:19Z
dc.date.issued2025
dc.description.abstractRationale and Objectives This study assesses the image quality of temporal bone ultra-high-resolution (UHR) Computed tomography (CT) scans in adults and children using hybrid iterative reconstruction (HIR) and a novel, vendor-specific deep learning-based reconstruction (DLR) algorithm called AiCE Inner Ear. Material and Methods In a retrospective, single-center study (February 1–July 30, 2023), UHR-CT scans of 57 temporal bones of 35 patients (5 children, 23 male) with at least one anatomical unremarkable temporal bone were included. There is an adult computed tomography dose index volume (CTDIvol 25.6 mGy) and a pediatric protocol (15.3 mGy). Images were reconstructed using HIR at normal resolution (0.5-mm slice thickness, 512² matrix) and UHR (0.25-mm, 1024² and 2048² matrix) as well as with a vendor-specific DLR advanced intelligent clear-IQ engine inner ear (AiCE Inner Ear) at UHR (0.25-mm, 1024² matrix). Three radiologists evaluated 18 anatomic structures using a 5-point Likert scale. Signal-to-noise (SNR) and contrast-to-noise ratio (CNR) were measured automatically. Results In the adult protocol subgroup (n = 30; median age: 51 [11–89]; 19 men) and the pediatric protocol subgroup (n = 5; median age: 2 [1–3]; 4 men), UHR-CT with DLR significantly improved subjective image quality (p<0.024), reduced noise (p<0.001), and increased CNR and SNR (p<0.001). DLR also enhanced visualization of key structures, including the tendon of the stapedius muscle (p<0.001), tympanic membrane (p<0.009), and basal aspect of the osseous spiral lamina (p<0.018). Conclusion Vendor-specific DLR-enhanced UHR-CT significantly improves temporal bone image quality and diagnostic performance.en
dc.identifier.doihttps://doi.org/10.25358/openscience-15245
dc.identifier.urihttps://openscience.ub.uni-mainz.de/handle/20.500.12030/15266
dc.language.isoeng
dc.rightsCC-BY-4.0
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subject.ddc610 Medizinde
dc.subject.ddc610 Medical sciencesen
dc.titleDeep learning-enhanced ultra-high-resolution CT imaging for superior temporal bone visualizationen
dc.typeZeitschriftenaufsatz
jgu.apc.netprice2387,63
jgu.apc.price2554,76
jgu.apc.taxrate7
jgu.apc.transformationcontractElsevier
jgu.dfg.year2025
jgu.identifier.uuidb8b30ae9-90ec-4136-b9b2-02b2af0f5cee
jgu.journal.issue6
jgu.journal.titleAcademic radiology
jgu.journal.volume32
jgu.nationalcurrency.eur2387,63
jgu.organisation.departmentFB 04 Medizin
jgu.organisation.nameJohannes Gutenberg-Universität Mainz
jgu.organisation.number2700
jgu.organisation.placeMainz
jgu.organisation.rorhttps://ror.org/023b0x485
jgu.pages.end3630
jgu.pages.start3618
jgu.publisher.doi10.1016/j.acra.2025.02.002
jgu.publisher.eissn1878-4046
jgu.publisher.nameElsevier
jgu.publisher.placePhiladelphia, Pa.
jgu.publisher.year2025
jgu.rights.accessrightsopenAccess
jgu.subject.ddccode610
jgu.subject.dfgLebenswissenschaften
jgu.type.dinitypeArticleen_GB
jgu.type.resourceText
jgu.type.versionPublished version

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