Autoren:	Agarwal, Komal Podder, Indrashis Cockerell, Clay J. Kassir, Martin Grabbe, Stephan Goldust, Mohamad
Titel:	Update on diagnosis and treatment of actinic keratosis
Online-Publikationsdatum:	23-Jan-2023
Erscheinungsdatum:	2022
Sprache des Dokuments:	Englisch
Zusammenfassung/Abstract:	Actinic keratosis (AK) is a relatively common skin condition occurring due to chronic sun-exposure, primarily affecting fair skin. Most dermatologists consider it an incipient malignancy due to its risk of full-blown malignant transformation to squamous cell carcinoma. However, the exact risk factors remain unknown, and thus its course cannot be predicted. Therefore, all cases of AK need early diagnosis and appropriate treatment to mitigate this risk. Over the years, several noninvasive diagnostic techniques such as dermoscopy, reflectance confocal microscopy, and newer treatment modalities (lesion-directed and field-directed) have been introduced with their own set of advantages and disadvantages. Notably, invasive skin biopsy with histopathology remains the gold-standard for diagnosis. Prevention is of paramount importance, highlighted by adequate sun-protection measures. This article reviews the diagnostic and treatment modalities of AK, with their latest updates, to optimize patient management.
DDC-Sachgruppe:	610 Medizin 610 Medical sciences
Veröffentlichende Institution:	Johannes Gutenberg-Universität Mainz
Organisationseinheit:	FB 04 Medizin
Veröffentlichungsort:	Mainz
ROR:	https://ror.org/023b0x485
DOI:	http://doi.org/10.25358/openscience-8627
Version:	Published version
Publikationstyp:	Zeitschriftenaufsatz
Nutzungsrechte:	CC BY
Informationen zu den Nutzungsrechten:	https://creativecommons.org/licenses/by/4.0/
Zeitschrift:	Dermatological reviews 3 6
Seitenzahl oder Artikelnummer:	359 368
Verlag:	Wiley
Verlagsort:	Oxford, UK
Erscheinungsdatum:	2022
ISSN:	2637-7489
DOI der Originalveröffentlichung:	10.1002/der2.121
Enthalten in den Sammlungen:	DFG-491381577-H