Please use this identifier to cite or link to this item: http://doi.org/10.25358/openscience-8454
Full metadata record
DC FieldValueLanguage
dc.contributor.authorKarampinis, Ioannis-
dc.contributor.authorGalata, Christian-
dc.contributor.authorArani, Alireza-
dc.contributor.authorGrilli, Maurizio-
dc.contributor.authorHetjens, Svetlana-
dc.contributor.authorSchackcloth, Michael-
dc.contributor.authorBuderi, Silviu-
dc.contributor.authorStamenovic, Davor-
dc.contributor.authorRoessner, Erich D.-
dc.date.accessioned2022-12-01T09:17:13Z-
dc.date.available2022-12-01T09:17:13Z-
dc.date.issued2021-
dc.identifier.urihttps://openscience.ub.uni-mainz.de/handle/20.500.12030/8470-
dc.description.abstractBackground Postoperative air leaks are a common complication after lung surgery. They are associated with prolonged hospital stay, increased postoperative pain and treatment costs. The treatment of prolonged air leaks remains controversial. Several treatments have been proposed including different types of sealants, chemical pleurodesis, or early surgical intervention. The aim of this review was to analyze the impact of autologous blood pleurodesis in a systematic way. Methods A systematic review of the literature was conducted until July 2020. Studies with more than five adult patients undergoing lung resections were included. Studies in patients receiving blood pleurodesis for pneumothorax were excluded. The search strategy included proper combinations of the MeSH terms “air leak”, “blood transfusion” and “lung surgery”. Results Ten studies with a total of 198 patients were included in the analysis. The pooled success rate for sealing the air leak within 48 h of the blood pleurodesis was 83.7% (95% CI: 75.7; 90.3). The pooled incidence of the post-interventional empyema was 1.5%, with a pooled incidence of post-interventional fever of 8.6%. Conclusions Current evidence supports the idea that autologous blood pleurodesis leads to a faster healing of postoperative air leaks than conservative treatment. The complication rate is very low. Formal recommendations on how to perform the procedure are not possible with the current evidence. A randomized controlled trial in the modern era is necessary to confirm the benefits.en_GB
dc.language.isoengde
dc.rightsCC BY-NC-ND*
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subject.ddc610 Medizinde_DE
dc.subject.ddc610 Medical sciencesen_GB
dc.titleAutologous blood pleurodesis for the treatment of postoperative air leaks : a systematic review and meta-analysisen_GB
dc.typeZeitschriftenaufsatzde
dc.identifier.doihttp://doi.org/10.25358/openscience-8454-
jgu.type.dinitypearticleen_GB
jgu.type.versionPublished versionde
jgu.type.resourceTextde
jgu.organisation.departmentFB 04 Medizinde
jgu.organisation.number2700-
jgu.organisation.nameJohannes Gutenberg-Universität Mainz-
jgu.rights.accessrightsopenAccess-
jgu.journal.titleThoracic cancerde
jgu.journal.volume12de
jgu.journal.issue20de
jgu.pages.start2648de
jgu.pages.end2654de
jgu.publisher.year2021-
jgu.publisher.nameWiley-Blackwellde
jgu.publisher.placeHoboken, NJ u.a.de
jgu.publisher.issn1759-7714de
jgu.organisation.placeMainz-
jgu.subject.ddccode610de
jgu.publisher.doi10.1111/1759-7714.14138de
jgu.organisation.rorhttps://ror.org/023b0x485-
Appears in collections:JGU-Publikationen

Files in This Item:
  File Description SizeFormat
Thumbnail
autologous_blood_pleurodesis_-20221201101417754.pdf929.53 kBAdobe PDFView/Open