Gutenberg Open Science: Reading the evolution of compartmentalization in the ribosome assembly toolbox : the YRG protein family

Please use this identifier to cite or link to this item: http://doi.org/10.25358/openscience-7979

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DC Field	Value	Language
dc.contributor.author	Mier, Pablo	-
dc.contributor.author	Pérez-Pulido, Antonio J.	-
dc.contributor.author	Reynaud, Emmanuel G.	-
dc.contributor.author	Andrade, Miguel	-
dc.date.accessioned	2022-10-13T09:25:40Z	-
dc.date.available	2022-10-13T09:25:40Z	-
dc.date.issued	2017
dc.identifier.uri	https://openscience.ub.uni-mainz.de/handle/20.500.12030/7994	-
dc.description.abstract	Reconstructing the transition from a single compartment bacterium to a highly compartmentalized eukaryotic cell is one of the most studied problems of evolutionary cell biology. However, timing and details of the establishment of compartmentalization are unclear and difficult to assess. Here, we propose the use of molecular markers specific to cellular compartments to set up a framework to advance the understanding of this complex intracellular process. Specifically, we use a protein family related to ribosome biogenesis, YRG (YlqF related GTPases), whose evolution is linked to the establishment of cellular compartments, leveraging the current genomic data. We analyzed orthologous proteins of the YRG family in a set of 171 proteomes for a total of 370 proteins. We identified ten YRG protein subfamilies that can be associated to six subcellular compartments (nuclear bodies, nucleolus, nucleus, cytosol, mitochondria, and chloroplast), and which were found in archaeal, bacterial and eukaryotic proteomes. Our analysis reveals organism streamlining related events in specific taxonomic groups such as Fungi. We conclude that the YRG family could be used as a compartmentalization marker, which could help to trace the evolutionary path relating cellular compartments with ribosome biogenesis.	en_GB
dc.description.sponsorship	DFG, Open Access-Publizieren Universität Mainz / Universitätsmedizin	de
dc.language.iso	eng	de
dc.rights	CC BY	*
dc.rights.uri	https://creativecommons.org/licenses/by/4.0/	*
dc.subject.ddc	570 Biowissenschaften	de_DE
dc.subject.ddc	570 Life sciences	en_GB
dc.title	Reading the evolution of compartmentalization in the ribosome assembly toolbox : the YRG protein family	en_GB
dc.type	Zeitschriftenaufsatz	de
dc.identifier.doi	http://doi.org/10.25358/openscience-7979	-
jgu.type.dinitype	article	en_GB
jgu.type.version	Published version	de
jgu.type.resource	Text	de
jgu.organisation.department	FB 10 Biologie	de
jgu.organisation.number	7970	-
jgu.organisation.name	Johannes Gutenberg-Universität Mainz	-
jgu.rights.accessrights	openAccess	-
jgu.journal.title	PLoS one	de
jgu.journal.volume	12	de
jgu.journal.issue	1	de
jgu.pages.alternative	e0169750	de
jgu.publisher.year	2017	-
jgu.publisher.name	PLoS	de
jgu.publisher.place	Lawrence, Kan.	de
jgu.publisher.uri	http://dx.doi.org/10.1371/journal.pone.0169750	de
jgu.publisher.issn	1932-6203	de
jgu.notes.public	Andrade, Miguel veröffentlicht unter: Andrade-Navarro, Miguel A.	de
jgu.organisation.place	Mainz	-
jgu.subject.ddccode	570	de
opus.date.modified	2018-05-18T09:21:29Z
opus.subject.dfgcode	00-000
opus.organisation.string	FB 10: Biologie: Institut für Organismische und Molekulare Evolutionsbiologie	de_DE
opus.identifier.opusid	56534
opus.institute.number	1011
opus.metadataonly	false
opus.type.contenttype	Keine	de_DE
opus.type.contenttype	None	en_EN
opus.affiliated	Mier, Pablo
opus.affiliated	Andrade, Miguel
jgu.publisher.doi	10.1371/journal.pone.0169750	de
jgu.organisation.ror	https://ror.org/023b0x485	-
Appears in collections:	DFG-OA-Publizieren (2012 - 2017)

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