Gutenberg Open Science: Cough is dangerous : neural correlates of implicit body symptoms associations

Please use this identifier to cite or link to this item: http://doi.org/10.25358/openscience-7819

Full metadata record

DC Field	Value	Language
dc.contributor.author	Mier, Daniela	-
dc.contributor.author	Witthöft, Michael	-
dc.contributor.author	Bailer, Josef	-
dc.contributor.author	Ofer, Julia	-
dc.contributor.author	Kerstner, Tobias	-
dc.contributor.author	Rist, Fred	-
dc.contributor.author	Diener, Carsten	-
dc.date.accessioned	2022-10-04T10:23:22Z	-
dc.date.available	2022-10-04T10:23:22Z	-
dc.date.issued	2016
dc.identifier.uri	https://openscience.ub.uni-mainz.de/handle/20.500.12030/7834	-
dc.description.abstract	The negative interpretation of body sensations (e.g., as sign of a severe illness) is a crucial cognitive process in pathological health anxiety (HA). However, little is known about the nature and the degree of automaticity of this interpretation bias. We applied an implicit association test (IAT) in 20 subjects during functional magnetic resonance imaging (fMRI) to investigate behavioral and neural correlates of implicit attitudes toward symptom words. On the behavioral level, body symptom words elicited strong negative implicit association effects, as indexed by slowed reaction times, when symptom words were paired with the attribute “harmless” (incongruent condition). fMRI revealed increased activation in the dorsolateral prefrontal cortex (DLPFC) and posterior parietal cortex for the comparison of incongruent words with control words, as well as with a lower significance threshold also in comparison to congruent words. Moreover, activation in the DLPFC, posterior parietal cortex, nucleus accumbens, and cerebellum varied with individual levels of HA (again, in comparison to control words, as well as with a lower significance threshold also in comparison to congruent words). Slowed reaction times as well as increased activation in dorsolateral prefrontal and posterior parietal cortex point to increased inhibitory demands during the incongruent IAT condition. The positive association between HA severity and neural activity in nucleus accumbens, dorsolateral prefrontal, and posterior parietal cortex suggests that HA is characterized by both intensified negative implicit attitudes and hampered cognitive control mechanisms when confronted with body symptoms.	en_GB
dc.description.sponsorship	DFG, Open Access-Publizieren Universität Mainz / Universitätsmedizin	de
dc.language.iso	eng	de
dc.rights	CC BY	*
dc.rights.uri	https://creativecommons.org/licenses/by/4.0/	*
dc.subject.ddc	150 Psychologie	de_DE
dc.subject.ddc	150 Psychology	en_GB
dc.title	Cough is dangerous : neural correlates of implicit body symptoms associations	en_GB
dc.type	Zeitschriftenaufsatz	de
dc.identifier.doi	http://doi.org/10.25358/openscience-7819	-
jgu.type.dinitype	article	en_GB
jgu.type.version	Published version	de
jgu.type.resource	Text	de
jgu.organisation.department	FB 02 Sozialwiss., Medien u. Sport	de
jgu.organisation.number	7910	-
jgu.organisation.name	Johannes Gutenberg-Universität Mainz	-
jgu.rights.accessrights	openAccess	-
jgu.journal.title	Frontiers in psychology	de
jgu.journal.volume	7	de
jgu.pages.alternative	Art. 247	de
jgu.publisher.year	2016	-
jgu.publisher.name	Frontiers Research Foundation	de
jgu.publisher.place	Lausanne	de
jgu.publisher.uri	http://dx.doi.org/10.3389/fpsyg.2016.00247	de
jgu.publisher.issn	1664-1078	de
jgu.organisation.place	Mainz	-
jgu.subject.ddccode	150	de
opus.date.modified	2018-08-22T10:00:35Z
opus.subject.dfgcode	00-000
opus.organisation.string	FB 02: Sozialwissenschaften, Medien und Sport: Psychologisches Institut	de_DE
opus.identifier.opusid	53816
opus.institute.number	0204
opus.metadataonly	false
opus.type.contenttype	Keine	de_DE
opus.type.contenttype	None	en_EN
opus.affiliated	Witthöft, Michael
jgu.publisher.doi	10.3389/fpsyg.2016.00247	de
jgu.organisation.ror	https://ror.org/023b0x485	-
Appears in collections:	DFG-OA-Publizieren (2012 - 2017)

Files in This Item:

	File	Description	Size	Format
	cough_is_dangerous___neural_c-20220914001624556.pdf		938.68 kB	Adobe PDF	View/Open

Show simple item record