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http://doi.org/10.25358/openscience-7611Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Hasenburg, Annette | - |
| dc.contributor.author | Plett, Hellmut | - |
| dc.contributor.author | Krämer, Bernhard | - |
| dc.contributor.author | Braicu, Elena | - |
| dc.contributor.author | Czogalla, Bastian | - |
| dc.contributor.author | Bossart, Michaela | - |
| dc.contributor.author | Singer, Susanne | - |
| dc.contributor.author | Mayr, Doris | - |
| dc.contributor.author | Staebler, Annette | - |
| dc.contributor.author | du Bois, Andreas | - |
| dc.contributor.author | Kommoss, Stefan | - |
| dc.contributor.author | Link, Theresa | - |
| dc.contributor.author | Burges, Alexander | - |
| dc.contributor.author | Heitz, Florian | - |
| dc.contributor.author | Keul, Jacqueline | - |
| dc.contributor.author | Trillsch, Fabian | - |
| dc.contributor.author | Harter, Philipp | - |
| dc.contributor.author | Wimberger, Pauline | - |
| dc.contributor.author | Buderath, Paul | - |
| dc.contributor.author | Klar, Maximilian | - |
| dc.date.accessioned | 2022-08-24T09:28:42Z | - |
| dc.date.available | 2022-08-24T09:28:42Z | - |
| dc.date.issued | 2021 | - |
| dc.identifier.uri | https://openscience.ub.uni-mainz.de/handle/20.500.12030/7625 | - |
| dc.description.abstract | Purpose Malignant ovarian germ cell (MOGCT) and sex cord stromal tumors (SCST) are ovarian neoplasms that affect disproportionally young women. Little is known about the impact of surgical and adjuvant management of these patient’s sexual life. This study investigated the effect of fertility-sparing surgery on sexual activity and global quality of life (gQoL) in women with MOGCT and SCST. Methods CORSETT was an observational, multicenter, mixed retrospective/prospective cohort study of the AGO study group. Women of any age who had been diagnosed with MOGCTs and SCSTs between 2001 and 2011 were asked to complete the Sexual Activity Questionnaire (SAQ) and the EORTC QLQ-C30. Results In total, 355 patients were included. Of these, 152 patients with confirmed histological diagnosis had completed the questionnaires. A total of 106 patients were diagnosed with SCST and 46 with MOGCT. Totally, 83 women (55%) were sexually active. After fertility-sparing surgery, patients had a 2.6 fold higher probability for being sexually active than after non-fertility-conserving treatment (unadjusted odds ratio (OR) 2.6, p = 0.01). After adjustment for age, time since diagnosis, FIGO stage, histology and phase of disease, the OR dropped to 1.8 (p = 0.22). Of the sexually active patients, 35 (42%) reported high levels of discomfort during intercourse; 38% after fertility-sparing; and 58% after non-fertility-sparing surgery (adjusted OR 2.8, p = 0.18). Women with fertility-conserving treatment reported a significantly better global QoL (Fadj 2.1, 6.2 points difference, p = 0.03) but not more pleasure during intercourse than women without fertility-sparing surgery (Fadj 0.4, p = 0.52). Conclusion Fertility preserving approaches should be offered to every patient, when oncologically acceptable. | en_GB |
| dc.language.iso | eng | de |
| dc.rights | CC BY | * |
| dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | * |
| dc.subject.ddc | 610 Medizin | de_DE |
| dc.subject.ddc | 610 Medical sciences | en_GB |
| dc.title | The effect of fertility-sparing surgery on sexuality and global quality of life in women with malignant ovarian germ cell and sex cord stromal tumors : an analysis of the CORSETT database of the AGO study group | en_GB |
| dc.type | Zeitschriftenaufsatz | de |
| dc.identifier.doi | http://doi.org/10.25358/openscience-7611 | - |
| jgu.type.dinitype | article | en_GB |
| jgu.type.version | Published version | de |
| jgu.type.resource | Text | de |
| jgu.organisation.department | FB 04 Medizin | de |
| jgu.organisation.number | 2700 | - |
| jgu.organisation.name | Johannes Gutenberg-Universität Mainz | - |
| jgu.rights.accessrights | openAccess | - |
| jgu.journal.title | Archives of gynecology and obstetrics | de |
| jgu.journal.volume | 304 | de |
| jgu.pages.start | 1541 | de |
| jgu.pages.end | 1549 | de |
| jgu.publisher.year | 2021 | - |
| jgu.publisher.name | Springer | de |
| jgu.publisher.place | Berlin u.a. | de |
| jgu.publisher.issn | 1432-0711 | de |
| jgu.organisation.place | Mainz | - |
| jgu.subject.ddccode | 610 | de |
| jgu.publisher.doi | 10.1007/s00404-021-06019-5 | de |
| jgu.organisation.ror | https://ror.org/023b0x485 | - |
| Appears in collections: | JGU-Publikationen | |
Files in This Item:
| File | Description | Size | Format | ||
|---|---|---|---|---|---|
 | the_effect_of_fertilitysparin-20220822155641186.pdf | 489.2 kB | Adobe PDF | View/Open |