Gutenberg Open Science: Gestörter Kerntransport und Phasentrennung von RNA-Bindeproteinen

Please use this identifier to cite or link to this item: http://doi.org/10.25358/openscience-7291

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DC Field	Value	Language
dc.contributor.author	Hutten, Saskia	-
dc.contributor.author	Dormann, Dorothee	-
dc.date.accessioned	2022-07-04T08:39:08Z	-
dc.date.available	2022-07-04T08:39:08Z	-
dc.date.issued	2021	-
dc.identifier.uri	https://openscience.ub.uni-mainz.de/handle/20.500.12030/7305	-
dc.description.abstract	Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are fatal neurodegenerative disordes, whose underlying molecular mechanisms are only beginning to emerge. A common molecular hallmark of both diseases is the relocalization of nuclear RNA-binding proteins (RBP) into cytoplasmic aggregates. Defects in nuclear import and aberrant phase separation appear to underlie RBP mislocalization and aggregation and could potentially be targeted in future therapies.	de_DE
dc.language.iso	ger	de
dc.rights	CC BY	*
dc.rights.uri	https://creativecommons.org/licenses/by/4.0/	*
dc.subject.ddc	570 Biowissenschaften	de_DE
dc.subject.ddc	570 Life sciences	en_GB
dc.title	Gestörter Kerntransport und Phasentrennung von RNA-Bindeproteinen	de_DE
dc.type	Zeitschriftenaufsatz	de
dc.identifier.doi	http://doi.org/10.25358/openscience-7291	-
jgu.type.dinitype	article	en_GB
jgu.type.version	Published version	de
jgu.type.resource	Text	de
jgu.organisation.department	FB 10 Biologie	de
jgu.organisation.number	7970	-
jgu.organisation.name	Johannes Gutenberg-Universität Mainz	-
jgu.rights.accessrights	openAccess	-
jgu.journal.title	Biospektrum	de
jgu.journal.volume	27	de
jgu.pages.start	365	de
jgu.pages.end	367	de
jgu.publisher.year	2021	-
jgu.publisher.name	Spektrum	de
jgu.publisher.place	Heidelberg	de
jgu.publisher.issn	1868-6249	de
jgu.organisation.place	Mainz	-
jgu.subject.ddccode	570	de
jgu.publisher.doi	10.1007/s12268-021-1599-z	de
jgu.organisation.ror	https://ror.org/023b0x485
Appears in collections:	JGU-Publikationen

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