Please use this identifier to cite or link to this item: http://doi.org/10.25358/openscience-7076
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dc.contributor.authorSchuster, Alexander Karl-Georg-
dc.contributor.authorKluck, Anne-Kristin-
dc.contributor.authorKorb, Christina A.-
dc.contributor.authorStoffelns, Bernhard-
dc.contributor.authorNickels, Stefan-
dc.contributor.authorSchulz, Andreas-
dc.contributor.authorMünzel, Thomas-
dc.contributor.authorWild, Philipp S.-
dc.contributor.authorBeutel, Manfred E.-
dc.contributor.authorSchmidtmann, Irene-
dc.contributor.authorLackner, Karl J.-
dc.contributor.authorPeto, Tunde-
dc.contributor.authorPfeiffer, Norbert-
dc.date.accessioned2022-06-02T10:12:25Z-
dc.date.available2022-06-02T10:12:25Z-
dc.date.issued2020-
dc.identifier.urihttps://openscience.ub.uni-mainz.de/handle/20.500.12030/7090-
dc.description.abstractPurpose We aimed to determine the prevalence of characteristics and pathologies of the vitreo-macular interface within the general population. Methods The Gutenberg Health Study is a population-based study in Germany, including an ophthalmological examination with refraction, biometry and optical coherence tomography (OCT) imaging. Characteristics of the vitreo-macular interface were graded on volume scans including visibility of an epiretinal membrane, full-thickness macular hole, lamellar hole and pseudohole. Overall and age-specific prevalences including 95% confidence intervals [95%-CI] were calculated. Association analyses were conducted to determine systemic and ocular factors that are associated with epiretinal membranes (the most common pathology) using multivariable logistic regression. Results A total of 1890 people aged 40–80 years were included in the study. Of these, 4.7% (95%-CI: 3.8%–5.8%) had an epiretinal membrane in at least one eye, 0.1% a full-thickness macular hole, 0.6% a lamellar hole and 0.6% a pseudohole. The presence of an epiretinal membrane was associated with higher age, myopic refractive error and prior retinal laser therapy, but not with gender, body height, body weight, smoking, prior cataract surgery or intraocular pressure. Conclusions Epiretinal membranes are more frequent in older and myopic subjects and in those with prior retinal laser therapy.en_GB
dc.language.isoengde
dc.rightsCC BY-NC-ND*
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subject.ddc610 Medizinde_DE
dc.subject.ddc610 Medical sciencesen_GB
dc.titleCharacteristics and pathologies of the vitreo-macular interface : results from the Gutenberg Health Studyen_GB
dc.typeZeitschriftenaufsatzde
dc.identifier.doihttp://doi.org/10.25358/openscience-7076-
jgu.type.dinitypearticleen_GB
jgu.type.versionPublished versionde
jgu.type.resourceTextde
jgu.organisation.departmentFB 04 Medizinde
jgu.organisation.number2700-
jgu.organisation.nameJohannes Gutenberg-Universität Mainz-
jgu.rights.accessrightsopenAccess-
jgu.journal.titleActa ophthalmologicade
jgu.journal.volume98de
jgu.journal.issue3de
jgu.pages.starte273de
jgu.pages.ende281de
jgu.publisher.year2020-
jgu.publisher.nameBlackwellde
jgu.publisher.placeOxfordde
jgu.publisher.issn1755-3768de
jgu.organisation.placeMainz-
jgu.subject.ddccode610de
jgu.publisher.doi10.1111/aos.14285de
jgu.organisation.rorhttps://ror.org/023b0x485
Appears in collections:JGU-Publikationen

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