Please use this identifier to cite or link to this item:
http://doi.org/10.25358/openscience-6285
Authors: | Ellwardt, Erik Geber, Christian Lotz, Johannes Birklein, Frank |
Title: | Heterogeneous presentation of caspr2 antibody-associated peripheral neuropathy : a case series |
Online publication date: | 16-Aug-2021 |
Year of first publication: | 2020 |
Language: | english |
Abstract: | Contactin-associated protein 2–like (caspr2) antibodies have been discovered recently. Since then a multitude of patients with caspr2 antibodies presenting with different neurological symptoms have been reported. Here, we describe three patients with caspr2 antibodies with different types of pain/no pain in combination with peripheral neuropathy. The first patient, a 33-year-old woman, presented with erythromelalgia-like pain and autonomic symptoms; the second patient, a 58-year-old man, with paresthesia and pain while walking together with signs of peripheral motor neuron hyperexcitability in combination with optic neuritis, and the third patient, a 74-year-old man, without any pain but with polyneuropathy and encephalopathy. These cases illustrate the spectrum of symptoms in anti-caspr2 diseases. The pain in such cases can be treated causally. |
DDC: | 610 Medizin 610 Medical sciences |
Institution: | Johannes Gutenberg-Universität Mainz |
Department: | FB 04 Medizin |
Place: | Mainz |
ROR: | https://ror.org/023b0x485 |
DOI: | http://doi.org/10.25358/openscience-6285 |
Version: | Published version |
Publication type: | Zeitschriftenaufsatz |
License: | CC BY |
Information on rights of use: | https://creativecommons.org/licenses/by/4.0/ |
Journal: | European journal of pain 24 7 |
Pages or article number: | 1411 1418 |
Publisher: | Wiley-Blackwell |
Publisher place: | Malden, Mass. u.a. |
Issue date: | 2020 |
ISSN: | 1532-2149 |
Publisher URL: | https://doi.org/10.1002/ejp.1572 |
Publisher DOI: | 10.1002/ejp.1572 |
Appears in collections: | JGU-Publikationen |
Files in This Item:
File | Description | Size | Format | ||
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ellwardt_erik-heterogeneous_-20210816112048594.pdf | 416.73 kB | Adobe PDF | View/Open |