Please use this identifier to cite or link to this item:
http://doi.org/10.25358/openscience-5812
Full metadata record
DC Field | Value | Language |
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dc.contributor.author | Hobbach, Anastasia J. | - |
dc.contributor.author | Closs, Ellen I. | - |
dc.date.accessioned | 2021-05-18T10:38:07Z | - |
dc.date.available | 2021-05-18T10:38:07Z | - |
dc.date.issued | 2020 | - |
dc.identifier.uri | https://openscience.ub.uni-mainz.de/handle/20.500.12030/5821 | - |
dc.description.abstract | A direct inhibiting effect of NO on the function of CAT-1 and -2A has been postulated to occur via nitrosylation of cysteine residues in the transporters. Neither the NO donor SNAP nor a mixture of SIN-1 and Spermine NONOate, that generates the strong nitrosating agent N2O3, reduced CAT-mediated L-arginine transport. Direct nitros(yl)ation does either not occur in CATs or does not affect their transport function. A regulatory effect of NO or nitrosating agents on CAT-mediated transport under physiological conditions seems, therefore, unlikely. | en_GB |
dc.language.iso | eng | de |
dc.rights | CC BY | * |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | * |
dc.subject.ddc | 610 Medizin | de_DE |
dc.subject.ddc | 610 Medical sciences | en_GB |
dc.title | Human cationic amino acid transporters are not affected by direct nitros(yl)ation | en_GB |
dc.type | Zeitschriftenaufsatz | de |
dc.identifier.doi | http://doi.org/10.25358/openscience-5812 | - |
jgu.type.dinitype | article | en_GB |
jgu.type.version | Published version | de |
jgu.type.resource | Text | de |
jgu.organisation.department | FB 04 Medizin | de |
jgu.organisation.number | 2700 | - |
jgu.organisation.name | Johannes Gutenberg-Universität Mainz | - |
jgu.rights.accessrights | openAccess | - |
jgu.journal.title | Amino acids | de |
jgu.journal.volume | 52 | de |
jgu.pages.start | 499 | de |
jgu.pages.end | 503 | de |
jgu.publisher.year | 2020 | - |
jgu.publisher.name | Springer | de |
jgu.publisher.place | Wien u.a. | de |
jgu.publisher.uri | https://doi.org/10.1007/s00726-020-02819-2 | de |
jgu.publisher.issn | 1438-2199 | de |
jgu.organisation.place | Mainz | - |
jgu.subject.ddccode | 610 | de |
jgu.publisher.doi | 10.1007/s00726-020-02819-2 | |
jgu.organisation.ror | https://ror.org/023b0x485 | |
Appears in collections: | JGU-Publikationen |
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File | Description | Size | Format | ||
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hobbach_anastasia-human_cationic-20210422213912095.pdf | 639.92 kB | Adobe PDF | View/Open |