Gutenberg Open Science: Epileptic seizure discharges in patients after open chamber cardiac surgery : a prospective prevalence pilot study using continuous electroencephalography

Please use this identifier to cite or link to this item: http://doi.org/10.25358/openscience-5764

Full metadata record

DC Field	Value	Language
dc.contributor.author	Tschernatsch, Marlene	-
dc.contributor.author	Juenemann, Martin	-
dc.contributor.author	Alhaidar, Fouad	-
dc.contributor.author	El Shazly, Jasmin	-
dc.contributor.author	Butz, Marius	-
dc.contributor.author	Meyer, Marco	-
dc.contributor.author	Gerriets, Tibo	-
dc.contributor.author	Schönburg, Markus	-
dc.contributor.author	Schramm, Patrick	-
dc.date.accessioned	2021-05-06T10:51:51Z	-
dc.date.available	2021-05-06T10:51:51Z	-
dc.date.issued	2020	-
dc.identifier.uri	https://openscience.ub.uni-mainz.de/handle/20.500.12030/5773	-
dc.description.abstract	PURPOSE Patients undergoing cardiac surgery often develop delirium which increases the risk of postoperative morbidity and leads to a reduced quality of life. Retrospective studies show a higher incidence of delirium in patients with seizures. However, these studies do not systematically detect subclinical seizures, so the incidence of seizures after cardiac surgery remains speculative. The objective of this study is to determine the prevalence of electrographic seizures after elective open-chamber cardiac surgery. METHODS This prospective, blinded, monocentric, observational study investigated patients scheduled for elective open-chamber valve reconstruction or replacement. Anaesthesia, surgery and postoperative treatment were standardized and not influenced by the presented observation. After surgery, all patients arrived at the ICU, and EEG monitoring started within the first hour. EEG recording was continuously performed for up to 24 h, and the results were independently analysed by two blinded EEG board-certified neurologists. RESULTS 100 patients were included. Abnormal EEG patterns were present in 33% of patients, and 9% of all patients showed electrographic seizures. The main EEG activity at the beginning of each recording was suppressed or showed a burst-suppression pattern, and at the end of recording, all patients had an alpha/theta rhythm. An association between electrographic seizures and delirium was found (pχ2 < 0.01). CONCLUSION This study reveals a surprisingly high incidence of abnormal EEG patterns and electrographic seizures in patients undergoing open-chamber cardiac surgery. As electrographic seizures are associated with the incidence of delirium, this finding is a relevant phenomenon in the post-cardiac surgery ICU population.	en_GB
dc.language.iso	eng	de
dc.rights	CC BY-NC	*
dc.rights.uri	https://creativecommons.org/licenses/by-nc/4.0/	*
dc.subject.ddc	610 Medizin	de_DE
dc.subject.ddc	610 Medical sciences	en_GB
dc.title	Epileptic seizure discharges in patients after open chamber cardiac surgery : a prospective prevalence pilot study using continuous electroencephalography	en_GB
dc.type	Zeitschriftenaufsatz	de
dc.identifier.doi	http://doi.org/10.25358/openscience-5764	-
jgu.type.dinitype	article	en_GB
jgu.type.version	Published version	de
jgu.type.resource	Text	de
jgu.organisation.department	FB 04 Medizin	de
jgu.organisation.number	2700	-
jgu.organisation.name	Johannes Gutenberg-Universität Mainz	-
jgu.rights.accessrights	openAccess	-
jgu.journal.title	Intensive care medicine	de
jgu.journal.volume	46	de
jgu.pages.start	1418	de
jgu.pages.end	1424	de
jgu.publisher.year	2020	-
jgu.publisher.name	Springer	de
jgu.publisher.place	Berlin u.a.	de
jgu.publisher.uri	https://doi.org/10.1007/s00134-020-06073-8	de
jgu.publisher.issn	1432-1238	de
jgu.organisation.place	Mainz	-
jgu.subject.ddccode	610	de
jgu.publisher.doi	10.1007/s00134-020-06073-8
jgu.organisation.ror	https://ror.org/023b0x485
Appears in collections:	JGU-Publikationen

Files in This Item:

	File	Description	Size	Format
	schramm_patrick-epileptic_seiz-20210420100958452.pdf		1.17 MB	Adobe PDF	View/Open

Show simple item record