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Results 1-10 of 11 (Search time: 0.009 seconds).
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PreviewIssue dateOnline publication dateTitleAuthor(s)
saeed_mohamed_e._m.-drug_repurposi-20210510114527807.pdf.jpg202110-May-2021Drug repurposing using transcriptome sequencing and virtual drug screening in a patient with glioblastomaSaeed, Mohamed E. M.; Kadioglu, Onat; Greten, Henry Johannes; Yildirim, Adem; Mayr, Katharina; Wenz, Frederik; Giordano, Frank; Efferth, Thomas
özenver_nadire-chemometric_an-20210209112718237.pdf.jpg20209-Feb-2021Chemometric and transcriptomic profiling, microtubule disruption and cell death induction by secalonic acid in tumor cellsÖzenver, Nadire; Dawood, Mona; Fleischer, Edmond; Klinger, Anette; Efferth, Thomas
kadioglu_onat-identification-20210209101413928.pdf.jpg20209-Feb-2021Identification of novel rare ABCC1 transporter mutations in tumor biopsies of cancer patientsKadioglu, Onat; Saeed, Mohamed; Munder, Markus; Spuller, Andreas; Greten, Henry Johannes; Efferth, Thomas
selection_of_safe_artemisinin-20220624130755185.pdf.jpg202127-Jun-2022Selection of safe artemisinin derivatives using a machine learning-based cardiotoxicity platform and in vitro and in vivo validationKadioglu, Onat; Klauck, Sabine M.; Fleischer, Edmond; Shan, Letian; Efferth, Thomas
pyrrolizidine_alkaloids_cause-20220701131337232.pdf.jpg20224-Jul-2022Pyrrolizidine alkaloids cause cell cycle and DNA damage repair defects as analyzed by transcriptomics in cytochrome P450 3A4-overexpressing HepG2 clone 9 cellsAbdelfatah, Sara; Naß, Janine; Knorz, Caroline; Klauck, Sabine M.; Küpper, Jan-Heiner; Efferth, Thomas
network_pharmacology_of_tript-20220729131545075.pdf.jpg20213-Aug-2022Network pharmacology of triptolide in cancer cells : implications for transcription factor bindingSeo, Ean-Jeong; Dawood, Mona; Hult, Annika K.; Olsson, Martin L.; Efferth, Thomas
the_immunosuppressive_activit-20221017113132463.pdf.jpg20219-Nov-2022The immunosuppressive activity of artemisinin-type drugs towards inflammatory and autoimmune diseasesEfferth, Thomas; Oesch, Franz
the_cardiac_glycoside_zinc253-20230815154227037.pdf.jpg202324-Aug-2023The cardiac glycoside ZINC253504760 induces parthanatos-type cell death and G2/M arrest via downregulation of MEK1/2 phosphorylation in leukemia cellsZhou, Min; Boulos, Joelle C.; Klauck, Sabine M.; Efferth, Thomas
cynaropicrin_disrupts_tubulin-20230815123736975.pdf.jpg202324-Aug-2023Cynaropicrin disrupts tubulin and c-Myc-related signaling and induces parthanatos-type cell death in multiple myelomaBoulos, Joelle C.; Omer, Ejlal A.; Rigano, Daniela; Formisano, Carmen; Chatterjee, Manik; Leich, Ellen; Klauck, Sabine M.; Shan, Le-tian; Efferth, Thomas
natural_products_targeting_tu-20240117111304722.pdf.jpg202317-Jan-2024Natural products targeting tumour angiogenesisLu, Xiaohua; Friedrich, Lara Johanna; Efferth, Thomas

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