Gutenberg Open Science: Electrochemical synthesis of isoxazoles and isoxazolines via anodic oxidation of oximes

Please use this identifier to cite or link to this item: http://doi.org/10.25358/openscience-9752

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DC Field	Value	Language
dc.contributor.author	Hofmann, Silja	-
dc.contributor.author	Winter, Johannes	-
dc.contributor.author	Prenzel, Tobias	-
dc.contributor.author	de Jesús Gálvez-Vázquez, María	-
dc.contributor.author	Waldvogel, Siegfried R.	-
dc.date.accessioned	2023-12-05T11:40:34Z	-
dc.date.available	2023-12-05T11:40:34Z	-
dc.date.issued	2023	-
dc.identifier.uri	https://openscience.ub.uni-mainz.de/handle/20.500.12030/9770	-
dc.description.abstract	Isoxazol(in)es are widely featured structural motifs in natural products, agrochemicals, and pharmaceuticals. The first intermolecular approach for a direct electrochemical synthesis from readily available aldoximes is reported. Isoxazoles and isoxazolines were obtained in yields up to 81 %. The synthesis is carried out in an undivided cell as the simplest electrochemical set-up and requires only the use of electric current as traceless oxidizing agent. The application of inexpensive and widely available electrode materials in combination with recyclable supporting electrolytes and solvents paves the path for translation of the presented reaction onto preparative scale. This is underlined by successful scale-up to multi-gram runs.	en_GB
dc.language.iso	eng	de
dc.rights	CC BY	*
dc.rights.uri	https://creativecommons.org/licenses/by/4.0/	*
dc.subject.ddc	540 Chemie	de_DE
dc.subject.ddc	540 Chemistry and allied sciences	en_GB
dc.title	Electrochemical synthesis of isoxazoles and isoxazolines via anodic oxidation of oximes	en_GB
dc.type	Zeitschriftenaufsatz	de
dc.identifier.doi	http://doi.org/10.25358/openscience-9752	-
jgu.type.dinitype	article	en_GB
jgu.type.version	Published version	de
jgu.type.resource	Text	de
jgu.organisation.department	FB 09 Chemie, Pharmazie u. Geowissensch.	de
jgu.organisation.number	7950	-
jgu.organisation.name	Johannes Gutenberg-Universität Mainz	-
jgu.rights.accessrights	openAccess	-
jgu.journal.title	ChemElectroChem	de
jgu.journal.volume	10	de
jgu.journal.issue	22	de
jgu.pages.alternative	e202300434	de
jgu.publisher.year	2023	-
jgu.publisher.name	Wiley-VCH	de
jgu.publisher.place	Weinheim	de
jgu.publisher.issn	2196-0216	de
jgu.organisation.place	Mainz	-
jgu.subject.ddccode	540	de
jgu.publisher.doi	10.1002/celc.202300434	de
jgu.organisation.ror	https://ror.org/023b0x485	-
jgu.subject.dfg	Naturwissenschaften	de
Appears in collections:	DFG-491381577-G

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