Gutenberg Open Science: Childhood glaucoma registry in Germany : initial database, clinical care and research (pilot study)

Please use this identifier to cite or link to this item: http://doi.org/10.25358/openscience-8754

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DC Field	Value	Language
dc.contributor.author	Aghayeva, Fidan A.	-
dc.contributor.author	Schuster, Alexander K.	-
dc.contributor.author	Diel, Heidi	-
dc.contributor.author	Chronopoulos, Panagiotis	-
dc.contributor.author	Wagner, Felix M.	-
dc.contributor.author	Grehn, Franz	-
dc.contributor.author	Pirlich, Nina	-
dc.contributor.author	Schweiger, Susann	-
dc.contributor.author	Pfeiffer, Norbert	-
dc.contributor.author	Hoffmann, Esther M.	-
dc.date.accessioned	2023-02-03T09:14:09Z	-
dc.date.available	2023-02-03T09:14:09Z	-
dc.date.issued	2022	-
dc.identifier.uri	https://openscience.ub.uni-mainz.de/handle/20.500.12030/8770	-
dc.description.abstract	Objective The aim of this prospective pilot study is to establish an initial database to register patients diagnosed with different types of childhood glaucoma and the set-up of a national registry for childhood glaucoma (ReCG) in Germany. 28 children with different types of diagnosed childhood glaucoma, who were admitted and treated at the Childhood Glaucoma Center of the University Medical Center Mainz, Germany were included. Main outcome measures were the type of childhood glaucoma, mean intraocular pressure (IOP) and genetic data of the patients. Results The documents and questionnaires for each individual included: informed consent form of the parents, medical history form of the child, patient’s gestational history questionnaire and general anesthesia examination form. Primary congenital and secondary childhood glaucoma were revealed in 11 (39%) and 17 (61%) patients, respectively. The mean IOP measured with Perkins tonometer in all patients under general anesthesia at the time of inclusion was 17.5 ± 11.8 mmHg in the right and 17 ± 8.9 mmHg in the left eyes. In 33% of children with glaucoma mutations in the CYP1B1, FOXC1, LTBP2 and TEK genes were found. The development of specific questionnaires for childhood glaucoma provides detailed baseline data to establish a ReCG in Germany for the first time.	en_GB
dc.description.sponsorship	Gefördert durch die Deutsche Forschungsgemeinschaft (DFG) - Projektnummer 491381577	de
dc.language.iso	eng	de
dc.rights	CC BY	*
dc.rights.uri	https://creativecommons.org/licenses/by/4.0/	*
dc.subject.ddc	610 Medizin	de_DE
dc.subject.ddc	610 Medical sciences	en_GB
dc.title	Childhood glaucoma registry in Germany : initial database, clinical care and research (pilot study)	en_GB
dc.type	Zeitschriftenaufsatz	de
dc.identifier.doi	http://doi.org/10.25358/openscience-8754	-
jgu.type.contenttype	Scientific article	de
jgu.type.dinitype	article	en_GB
jgu.type.version	Published version	de
jgu.type.resource	Text	de
jgu.organisation.department	FB 04 Medizin	de
jgu.organisation.number	2700	-
jgu.organisation.name	Johannes Gutenberg-Universität Mainz	-
jgu.rights.accessrights	openAccess	-
jgu.journal.title	BMC Research Notes	de
jgu.journal.volume	15	de
jgu.pages.alternative	32	de
jgu.publisher.year	2022	-
jgu.publisher.name	BMC	de
jgu.publisher.place	London	de
jgu.publisher.issn	1756-0500	de
jgu.organisation.place	Mainz	-
jgu.subject.ddccode	610	de
jgu.publisher.doi	10.1186/s13104-022-05921-8	de
jgu.organisation.ror	https://ror.org/023b0x485	-
jgu.subject.dfg	Lebenswissenschaften	de
Appears in collections:	DFG-491381577-G

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