Gutenberg Open Science: Anterior chamber angle in adults born extremely, very, and moderately preterm with and without retinopathy of prematurity : results of the Gutenberg Prematurity Eye Study

Please use this identifier to cite or link to this item: http://doi.org/10.25358/openscience-8668

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DC Field	Value	Language
dc.contributor.author	Fieß, Achim	-
dc.contributor.author	Gißler, Sandra	-
dc.contributor.author	Mildenberger, Eva	-
dc.contributor.author	Urschitz, Michael S.	-
dc.contributor.author	Fauer, Agnes	-
dc.contributor.author	Elflein, Heike M.	-
dc.contributor.author	Zepp, Fred	-
dc.contributor.author	Stoffelns, Bernhard	-
dc.contributor.author	Pfeiffer, Norbert	-
dc.contributor.author	Schuster, Alexander K.	-
dc.date.accessioned	2023-02-13T10:18:32Z	-
dc.date.available	2023-02-13T10:18:32Z	-
dc.date.issued	2022	-
dc.identifier.uri	https://openscience.ub.uni-mainz.de/handle/20.500.12030/8684	-
dc.description.abstract	Purpose: To determine whether prematurity and associated factors affect the anterior chamber angle (ACA) width in adulthood. Methods: The Gutenberg Prematurity Eye Study (GPES) is a retrospective cohort study with a prospective ophthalmologic examination of adults (age 18–52 years) in Germany. All participants were examined with Scheimpflug imaging (Pentacam HR, Oculus Optikgeräte GmbH, Wetzlar, Germany) using linear regression analysis to assess the associations of ACA in the different sectors with gestational age (GA), birth weight, birth weight percentile, retinopathy of prematurity (ROP), ROP treatment, placental insufficiency, preeclampsia, and breastfeeding. Results: In total, 516 eyes of 319 preterm and full-term individuals (aged 28.9 ± 8.8 years, 188 females) were examined. ROP treatment was associated with smaller ACA width in the nasal (B = −9.6 [95%CI: −14.7; −4.5] degree; p < 0.001) and temporal positions (B = −11.5 [95%CI: −17.7; −5.3] degree; p = 0.001), whereas non-treated individuals with ROP had an unaltered ACA width, as did individuals with low gestational age without ROP. Conclusion: Advanced stages of ROP following treatment with laser- and cryocoagulation lead to a smaller ACA width until adulthood, and hence may increase the risk of angle closure in later life.	en_GB
dc.description.sponsorship	Gefördert durch die Deutsche Forschungsgemeinschaft (DFG) - Projektnummer 491381577	de
dc.language.iso	eng	de
dc.rights	CC BY	*
dc.rights.uri	https://creativecommons.org/licenses/by/4.0/	*
dc.subject.ddc	610 Medizin	de_DE
dc.subject.ddc	610 Medical sciences	en_GB
dc.title	Anterior chamber angle in adults born extremely, very, and moderately preterm with and without retinopathy of prematurity : results of the Gutenberg Prematurity Eye Study	en_GB
dc.type	Zeitschriftenaufsatz	de
dc.identifier.doi	http://doi.org/10.25358/openscience-8668	-
jgu.type.contenttype	Scientific article	de
jgu.type.dinitype	article	en_GB
jgu.type.version	Published version	de
jgu.type.resource	Text	de
jgu.organisation.department	FB 04 Medizin	de
jgu.organisation.number	2700	-
jgu.organisation.name	Johannes Gutenberg-Universität Mainz	-
jgu.rights.accessrights	openAccess	-
jgu.journal.title	Children	de
jgu.journal.volume	9	de
jgu.journal.issue	2	de
jgu.pages.alternative	281	de
jgu.publisher.year	2022	-
jgu.publisher.name	MDPI	de
jgu.publisher.place	Basel	de
jgu.publisher.issn	2227-9067	de
jgu.organisation.place	Mainz	-
jgu.subject.ddccode	610	de
jgu.publisher.doi	10.3390/children9020281	de
jgu.organisation.ror	https://ror.org/023b0x485	-
jgu.subject.dfg	Lebenswissenschaften	de
Appears in collections:	DFG-491381577-G

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