Please use this identifier to cite or link to this item:
http://doi.org/10.25358/openscience-10170Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Minarrieta, Lucía | - |
| dc.contributor.author | Godoy, Gloria J. | - |
| dc.contributor.author | Velazquez, Lis N. | - |
| dc.contributor.author | Ghorbani, Peyman | - |
| dc.contributor.author | Sparwasser, Tim | - |
| dc.contributor.author | Berod, Luciana | - |
| dc.date.accessioned | 2024-03-08T14:02:23Z | - |
| dc.date.available | 2024-03-08T14:02:23Z | - |
| dc.date.issued | 2022 | - |
| dc.identifier.uri | https://openscience.ub.uni-mainz.de/handle/20.500.12030/10188 | - |
| dc.description.abstract | The CD11c+MHCII+ compartment within GM-CSF cultures consists of a MHCIIlowCD11bhigh population (GM-Macs) and a MHCIIhighCD11bint population (GM-DCs), with different metabolic profiles. GM-Macs upregulate iNOS and produce nitric oxide (NO) upon TLR activation inhibiting mitochondrial respiration (OXPHOS) while promoting glycolytic metabolism in GM-DCs, which naturally do not express iNOS. | en_GB |
| dc.language.iso | eng | de |
| dc.rights | CC BY-NC-ND | * |
| dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
| dc.subject.ddc | 610 Medizin | de_DE |
| dc.subject.ddc | 610 Medical sciences | en_GB |
| dc.title | Regulation of DC metabolism by nitric oxide in murine GM-CSF cultures | en_GB |
| dc.type | Zeitschriftenaufsatz | de |
| dc.identifier.doi | http://doi.org/10.25358/openscience-10170 | - |
| jgu.type.contenttype | Other | de |
| jgu.type.dinitype | article | en_GB |
| jgu.type.version | Published version | de |
| jgu.type.resource | Text | de |
| jgu.organisation.department | FB 04 Medizin | de |
| jgu.organisation.number | 2700 | - |
| jgu.organisation.name | Johannes Gutenberg-Universität Mainz | - |
| jgu.rights.accessrights | openAccess | - |
| jgu.journal.title | European journal of immunology | de |
| jgu.journal.volume | 53 | de |
| jgu.journal.issue | 2 | de |
| jgu.pages.alternative | 2149691 | de |
| jgu.publisher.year | 2022 | - |
| jgu.publisher.name | Wiley | de |
| jgu.publisher.place | Weinheim | de |
| jgu.publisher.issn | 1521-4141 | de |
| jgu.organisation.place | Mainz | - |
| jgu.subject.ddccode | 610 | de |
| jgu.publisher.doi | 10.1002/eji.202149691 | de |
| jgu.organisation.ror | https://ror.org/023b0x485 | - |
| jgu.subject.dfg | Lebenswissenschaften | de |
| Appears in collections: | DFG-491381577-H | |
Files in This Item:
| File | Description | Size | Format | ||
|---|---|---|---|---|---|
 | regulation_of_dc_metabolism_b-20240308145959753.pdf | 920.67 kB | Adobe PDF | View/Open |