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PreviewIssue dateOnline publication dateTitleAuthor(s)
59109.pdf.jpg201917-Jun-2019Identification of a potential allosteric site of Golgi α-mannosidase II using computer-aided drug designIrsheid, Lina; Wehler, Thomas; Borek, Christoph; Kiefer, Werner; Brenk, Ruth; Ortiz-Soto, Maria Elena; Seibel, Jürgen; Schirmeister, Tanja
barthels_fabian-banδit__b’-fac-20210628203840983.pdf.jpg202129-Jun-2021BANΔIT: B’-factor analysis for drug design and structural biologyBarthels, Fabian; Schirmeister, Tanja; Kersten, Christian
barthels_fabian-asymmetric_dis-20210805114859449.pdf.jpg202013-Aug-2021Asymmetric disulfanylbenzamides as irreversible and selective inhibitors of Staphylococcus aureus sortase ABarthels, Fabian; Marincola, Gabriella; Marciniak, Tessa; Konhäuser, Matthias; Hammerschmidt, Stefan; Bierlmeier, Jan; Distler, Ute; Wich, Peter R.; Tenzer, Stefan; Schwarzer, Dirk; Ziebuhr, Wilma; Schirmeister, Tanja
identification_of_plakortide_-20220510090302657.pdf.jpg201410-May-2022Identification of plakortide E from the Caribbean sponge Plakortis halichondroides as a trypanocidal protease inhibitor using bioactivity-guided fractionationOli, Swarna; Abdelmohsen, Usama Ramadan; Hentschel, Ute; Schirmeister, Tanja
novel_dengue_virus_ns2bns3_pr-20220913202020725.pdf.jpg20157-Dec-2022Novel dengue virus NS2B/NS3 protease inhibitorsWu, Hongmei; Bock, Stefanie; Snitko, Mariya; Berger, Thilo; Weidner, Thomas; Holloway, Steven; Kanitz, Manuel; Diederich, Wibke E.; Steuber, Holger; Walter, Christof; Hofmann, Daniela; Weißbrich, Benedikt; Spannaus, Ralf; Acosta, Eliana G.; Bartenschlager, Ralf; Engels, Bernd; Schirmeister, Tanja; Bodem, Jochen
cytotoxicity_of_endoperoxides-20220925182710959.pdf.jpg201721-Oct-2022Cytotoxicity of endoperoxides from the Caribbean sponge Plakortis halichondrioides towards sensitive and multidrug-resistant leukemia cells : acids vs. esters activity evaluationSchirmeister, Tanja; Oli, Swarna; Wu, Hongmei; Della Sala, Gerardo; Costantino, Valeria; Seo, Ean-Jeong; Efferth, Thomas
welker_armin-structure-acti-20210621155711267.pdf.jpg202128-Jun-2021Structure-activity relationships of benzamides and isoindolines designed as SARS-CoV protease inhibitors effective against SARS-CoV-2Welker, Armin; Kersten, Christian; Müller, Christin; Madhugiri, Ramakanth; Zimmer, Collin; Müller, Patrick; Zimmermann, Robert; Hammerschmidt, Stefan; Maus, Hannah; Ziebuhr, John; Sotriffer, Christoph; Schirmeister, Tanja
analysis_of_hyperforin_st_joh-20230118131954936.pdf.jpg202218-Jan-2023Analysis of hyperforin (St. John’s wort) action at TRPC6 channel leads to the development of a new class of antidepressant drugsEl Hamdaoui, Yamina; Zheng, Fang; Fritz, Nikolas; Ye, Lian; Tran, Mai Anh; Schwickert, Kevin; Schirmeister, Tanja; Braeuning, Albert; Lichtenstein, Dajana; Hellmich, Ute A.; Weikert, Dorothee; Heinrich, Markus; Treccani, Giulia; Schäfer, Michael K. E.; Nowak, Gabriel; Nürnberg, Bernd; Alzheimer, Christian; Müller, Christian P.; Friedland, Kristina
next_generation_of_fluorometr-20230914114142028.pdf.jpg202314-Sep-2023Next generation of fluorometric protease assays : 7-nitrobenz-2-oxa-1,3-diazol-4-yl-amides (NBD-amides) as class-spanning protease substratesMaus, Hannah; Müller, Patrick; Meta, Mergim; Hoba, Sabrina N.; Hammerschmidt, Stefan J.; Zimmermann, Robert A.; Zimmer, Collin; Fuchs, Natalie; Schirmeister, Tanja; Barthels, Fabian
subnanomolar_cathepsin_s_inhi-20230901153132231.pdf.jpg202312-Sep-2023Subnanomolar cathepsin S inhibitors with high selectivity : optimizing covalent reversible α-fluorovinylsulfones and α-sulfonates as potential immunomodulators cancerFuchs, Natalie; Meta, Mergim; Lantzberg, Bellinda; Bros, Matthias; Kuan, Seah Ling; Weil, Tanja; Schirmeister, Tanja

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