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Results 1-10 of 13 (Search time: 0.008 seconds).
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PreviewIssue dateOnline publication dateTitleAuthor(s)
barthels_fabian-banδit__b’-fac-20210628203840983.pdf.jpg202129-Jun-2021BANΔIT: B’-factor analysis for drug design and structural biologyBarthels, Fabian; Schirmeister, Tanja; Kersten, Christian
barthels_fabian-asymmetric_dis-20210805114859449.pdf.jpg202013-Aug-2021Asymmetric disulfanylbenzamides as irreversible and selective inhibitors of Staphylococcus aureus sortase ABarthels, Fabian; Marincola, Gabriella; Marciniak, Tessa; Konhäuser, Matthias; Hammerschmidt, Stefan; Bierlmeier, Jan; Distler, Ute; Wich, Peter R.; Tenzer, Stefan; Schwarzer, Dirk; Ziebuhr, Wilma; Schirmeister, Tanja
welker_armin-structure-acti-20210621155711267.pdf.jpg202128-Jun-2021Structure-activity relationships of benzamides and isoindolines designed as SARS-CoV protease inhibitors effective against SARS-CoV-2Welker, Armin; Kersten, Christian; Müller, Christin; Madhugiri, Ramakanth; Zimmer, Collin; Müller, Patrick; Zimmermann, Robert; Hammerschmidt, Stefan; Maus, Hannah; Ziebuhr, John; Sotriffer, Christoph; Schirmeister, Tanja
analysis_of_hyperforin_st_joh-20230118131954936.pdf.jpg202218-Jan-2023Analysis of hyperforin (St. John’s wort) action at TRPC6 channel leads to the development of a new class of antidepressant drugsEl Hamdaoui, Yamina; Zheng, Fang; Fritz, Nikolas; Ye, Lian; Tran, Mai Anh; Schwickert, Kevin; Schirmeister, Tanja; Braeuning, Albert; Lichtenstein, Dajana; Hellmich, Ute A.; Weikert, Dorothee; Heinrich, Markus; Treccani, Giulia; Schäfer, Michael K. E.; Nowak, Gabriel; Nürnberg, Bernd; Alzheimer, Christian; Müller, Christian P.; Friedland, Kristina
next_generation_of_fluorometr-20230914114142028.pdf.jpg202314-Sep-2023Next generation of fluorometric protease assays : 7-nitrobenz-2-oxa-1,3-diazol-4-yl-amides (NBD-amides) as class-spanning protease substratesMaus, Hannah; Müller, Patrick; Meta, Mergim; Hoba, Sabrina N.; Hammerschmidt, Stefan J.; Zimmermann, Robert A.; Zimmer, Collin; Fuchs, Natalie; Schirmeister, Tanja; Barthels, Fabian
subnanomolar_cathepsin_s_inhi-20230901153132231.pdf.jpg202312-Sep-2023Subnanomolar cathepsin S inhibitors with high selectivity : optimizing covalent reversible α-fluorovinylsulfones and α-sulfonates as potential immunomodulators cancerFuchs, Natalie; Meta, Mergim; Lantzberg, Bellinda; Bros, Matthias; Kuan, Seah Ling; Weil, Tanja; Schirmeister, Tanja
sarscovplproinhibitoren_als_m-20220701134011960.pdf.jpg20214-Jul-2022SARS-CoV-PLpro-Inhibitoren als mögliche Breitspektrum-VirostatikaHammerschmidt, Stefan Josef; Müller, Patrick; Schirmeister, Tanja
59874.pdf.jpg202023-Jun-2020Naphthoquinones as covalent reversible inhibitors of cysteine proteases : studies on inhibition mechanism and kineticsKlein, Philipp; Barthels, Fabian; Johe, Patrick; Wagner, Annika; Tenzer, Stefan; Distler, Ute; Le, Thien Anh; Schmid, Paul; Engel, Volker; Engels, Bernd; Hellmich, Ute; Opatz, Till; Schirmeister, Tanja
59826.pdf.jpg202018-May-2020New cysteine protease inhibitors : electrophilic (het)arenes and unexpected prodrug identification for the trypanosoma protease rhodesainKlein, Philipp; Johe, Patrick; Wagner, Annika; Jung, Sascha; Kühlborn, Jonas; Barthels, Fabian; Tenzer, Stefan; Distler, Ute; Waigel, Waldemar; Engels, Bernd; Hellmich, Ute; Opatz, Till; Schirmeister, Tanja
chemical_space_virtual_screen-20230418075719562.pdf.jpg202318-Apr-2023Chemical space virtual screening against hard-to-drug RNA methyltransferases DNMT2 and NSUN6Zimmermann, Robert A.; Fischer, Tim R.; Schwickert, Marvin; Nidoieva, Zarina; Schirmeister, Tanja; Kersten, Christian

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