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VorschauErscheinungsdatumOnline-PublikationsdatumTitelBeteiligte Person(en)
targeting_angiogenesis_by_phy-20220715121718964.pdf.jpg201315-Jul-2022Targeting angiogenesis by phytochemicalsKadioglu, Onat; Seo, Ean Jeong; Efferth, Thomas
prediction_of_cancer_drug_res-20220913190849926.pdf.jpg201514-Sep-2022Prediction of cancer drug resistance and implications for personalized medicineVolm, Manfred; Efferth, Thomas
cynaropicrin_disrupts_tubulin-20230815123736975.pdf.jpg202324-Aug-2023Cynaropicrin disrupts tubulin and c-Myc-related signaling and induces parthanatos-type cell death in multiple myelomaBoulos, Joelle C.; Omer, Ejlal A.; Rigano, Daniela; Formisano, Carmen; Chatterjee, Manik; Leich, Ellen; Klauck, Sabine M.; Shan, Le-tian; Efferth, Thomas
the_cardiac_glycoside_zinc253-20230815154227037.pdf.jpg202324-Aug-2023The cardiac glycoside ZINC253504760 induces parthanatos-type cell death and G2/M arrest via downregulation of MEK1/2 phosphorylation in leukemia cellsZhou, Min; Boulos, Joelle C.; Klauck, Sabine M.; Efferth, Thomas
dawood_mona-collateral_sen-20200928110332836.pdf.jpg201913-Jun-2019Collateral sensitivity of parthenolide via NF-κB and HIF-α inhibition and epigenetic changes in drug-resistant cancer cell linesDawood, Mona; Ooko, Edna; Efferth, Thomas
selection_of_safe_artemisinin-20220624130755185.pdf.jpg202127-Jun-2022Selection of safe artemisinin derivatives using a machine learning-based cardiotoxicity platform and in vitro and in vivo validationKadioglu, Onat; Klauck, Sabine M.; Fleischer, Edmond; Shan, Letian; Efferth, Thomas
identification_of_potential_n-20220701123610800.pdf.jpg20214-Jul-2022Identification of potential novel drug resistance mechanisms by genomic and transcriptomic profiling of colon cancer cells with p53 deletionKadioglu, Onat; Saeed, Mohamed; Mahmoud, Nuha; Azawi, Shaymaa; Mrasek, Kristin; Liehr, Thomas; Efferth, Thomas
pyrrolizidine_alkaloids_cause-20220701131337232.pdf.jpg20224-Jul-2022Pyrrolizidine alkaloids cause cell cycle and DNA damage repair defects as analyzed by transcriptomics in cytochrome P450 3A4-overexpressing HepG2 clone 9 cellsAbdelfatah, Sara; Naß, Janine; Knorz, Caroline; Klauck, Sabine M.; Küpper, Jan-Heiner; Efferth, Thomas
a_novel_ligand_of_the_transla-20220701124103992.pdf.jpg20214-Jul-2022A novel ligand of the translationally controlled tumor protein (TCTP) identified by virtual drug screening for cancer differentiation therapyFischer, Nicolas; Seo, Ean-Jeong; Abdelfatah, Sara; Fleischer, Edmond; Klinger, Anette; Efferth, Thomas
cytotoxicity_of_endoperoxides-20220925182710959.pdf.jpg201721-Okt-2022Cytotoxicity of endoperoxides from the Caribbean sponge Plakortis halichondrioides towards sensitive and multidrug-resistant leukemia cells : acids vs. esters activity evaluationSchirmeister, Tanja; Oli, Swarna; Wu, Hongmei; Della Sala, Gerardo; Costantino, Valeria; Seo, Ean-Jeong; Efferth, Thomas

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