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Results 1-10 of 23 (Search time: 0.01 seconds).
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PreviewIssue dateOnline publication dateTitleAuthor(s)
cynaropicrin_disrupts_tubulin-20230815123736975.pdf.jpg202324-Aug-2023Cynaropicrin disrupts tubulin and c-Myc-related signaling and induces parthanatos-type cell death in multiple myelomaBoulos, Joelle C.; Omer, Ejlal A.; Rigano, Daniela; Formisano, Carmen; Chatterjee, Manik; Leich, Ellen; Klauck, Sabine M.; Shan, Le-tian; Efferth, Thomas
the_cardiac_glycoside_zinc253-20230815154227037.pdf.jpg202324-Aug-2023The cardiac glycoside ZINC253504760 induces parthanatos-type cell death and G2/M arrest via downregulation of MEK1/2 phosphorylation in leukemia cellsZhou, Min; Boulos, Joelle C.; Klauck, Sabine M.; Efferth, Thomas
the_immunosuppressive_activit-20221017113132463.pdf.jpg20219-Nov-2022The immunosuppressive activity of artemisinin-type drugs towards inflammatory and autoimmune diseasesEfferth, Thomas; Oesch, Franz
3261.pdf.jpg201231-Jan-2013Shikonin directly targets mitochondria and causes mitochondrial dysfunction in cancer cellsWiench, Benjamin; Eichhorn, Tolga; Paulsen, Malte; Efferth, Thomas
dawood_mona-collateral_sen-20200928110332836.pdf.jpg201913-Jun-2019Collateral sensitivity of parthenolide via NF-κB and HIF-α inhibition and epigenetic changes in drug-resistant cancer cell linesDawood, Mona; Ooko, Edna; Efferth, Thomas
cytotoxicity_of_the_sesquiter-20220925164201931.pdf.jpg201517-Oct-2022Cytotoxicity of the sesquiterpene lactones neoambrosin and damsin from ambrosia maritima against multidrug-resistant cancer cellsSaaed, Mohamed; Jacob, Stefan; Sandjo, Louis P.; Sugimoto, Yoshikazu; Khalid, Hassan E.; Opatz, Till; Thines, Eckhard; Efferth, Thomas
pyrrolizidine_alkaloids_cause-20220701131337232.pdf.jpg20224-Jul-2022Pyrrolizidine alkaloids cause cell cycle and DNA damage repair defects as analyzed by transcriptomics in cytochrome P450 3A4-overexpressing HepG2 clone 9 cellsAbdelfatah, Sara; Naß, Janine; Knorz, Caroline; Klauck, Sabine M.; Küpper, Jan-Heiner; Efferth, Thomas
a_novel_ligand_of_the_transla-20220701124103992.pdf.jpg20214-Jul-2022A novel ligand of the translationally controlled tumor protein (TCTP) identified by virtual drug screening for cancer differentiation therapyFischer, Nicolas; Seo, Ean-Jeong; Abdelfatah, Sara; Fleischer, Edmond; Klinger, Anette; Efferth, Thomas
identification_of_potential_n-20220701123610800.pdf.jpg20214-Jul-2022Identification of potential novel drug resistance mechanisms by genomic and transcriptomic profiling of colon cancer cells with p53 deletionKadioglu, Onat; Saeed, Mohamed; Mahmoud, Nuha; Azawi, Shaymaa; Mrasek, Kristin; Liehr, Thomas; Efferth, Thomas
network_pharmacology_of_tript-20220729131545075.pdf.jpg20213-Aug-2022Network pharmacology of triptolide in cancer cells : implications for transcription factor bindingSeo, Ean-Jeong; Dawood, Mona; Hult, Annika K.; Olsson, Martin L.; Efferth, Thomas

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