Please use this identifier to cite or link to this item: http://doi.org/10.25358/openscience-759
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dc.contributor.authorHopf, Susanne-
dc.contributor.authorLiesenfeld, Matthias-
dc.contributor.authorSchmidtmann, Irene-
dc.contributor.authorAshayer, Shahrzad-
dc.contributor.authorPitz, Susanne-
dc.date.accessioned2018-11-26T14:51:48Z-
dc.date.available2018-11-26T15:51:48Z-
dc.date.issued2018-
dc.identifier.urihttps://openscience.ub.uni-mainz.de/handle/20.500.12030/761-
dc.description.abstractPurpose There is some controversy whether or not saccades change with age. This cross- sectional study aims to clarify the characteristics of reflexive saccades at various ages to establish a normative cohort in a standardized set-up. Second objective is to investigate the feasibility of saccadometry in daily ophthalmological practice. Methods One hundred healthy participants aged between 6 and 76 years underwent an ophthalmologic examination and saccadometry, using an infrared video-oculography device, sampling at 220 Hz. The reflexive saccades were evoked in four directions and three target displacements each (5°/15°/30° horizontally and of 5°/10°/20° vertically). Saccadic peak velocity, gain (amplitude/target displacement) and latency were measured. Results Mean peak velocity of saccades was 213°/s (± 29°/s), 352°/s (± 50°/s) and 455°/s (± 67°/s) to a target position 5°, 15°and 30° horizontally, respectively, and 208°/s (± 36°/s), 303°/s (± 50°/s) and 391°/s (± 71°/s) to a target position 5°, 10° and 20° vertically. The association between peak velocity and eccentricity proved to be present at any age in all four directions. We found no relevant effect of age on peak velocity, gain and latency in a fitted linear mixed model. However, latency becomes shorter during childhood and adolescence, while in adulthood it is relatively stable with a slight trend to increase in the elderly. Saccades are more precise when the target displacement is small. Isometric saccades are most common, followed by hypometric ones. All children and elderly were able to perform good quality saccadometry in a recording time of approximately 10 minutes. Conclusion The presented data may serve as normative control for further studies using such a video-oculography device for saccadometry. The means of peak velocity and the gain can be used independently from age respecting the target displacement. Latency is susceptible to age.en_GB
dc.description.sponsorshipDFG, Open Access-Publizieren Universität Mainz / Universitätsmedizin-
dc.language.isoeng-
dc.rightsCC BYde_DE
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/-
dc.subject.ddc610 Medizinde_DE
dc.subject.ddc610 Medical sciencesen_GB
dc.titleAge dependent normative data of vertical and horizontal reflexive saccadesen_GB
dc.typeZeitschriftenaufsatzde_DE
dc.identifier.doihttp://doi.org/10.25358/openscience-759-
jgu.type.dinitypearticle-
jgu.type.versionPublished versionen_GB
jgu.type.resourceText-
jgu.organisation.departmentFB 04 Medizin-
jgu.organisation.number2700-
jgu.organisation.nameJohannes Gutenberg-Universität Mainz-
jgu.rights.accessrightsopenAccess-
jgu.journal.titlePLOS ONE-
jgu.journal.volume13-
jgu.journal.issue9-
jgu.pages.alternativee0204008-
jgu.publisher.year2018-
jgu.publisher.namePLOS-
jgu.publisher.placeSan Francisco, California, US-
jgu.publisher.urihttp://dx.doi.org/10.1371/journal.pone.0204008-
jgu.publisher.issn1932-6203-
jgu.organisation.placeMainz-
jgu.subject.ddccode610-
opus.date.accessioned2018-11-26T14:51:48Z-
opus.date.modified2018-12-05T08:28:16Z-
opus.date.available2018-11-26T15:51:48-
opus.subject.dfgcode00-000-
opus.organisation.stringFB 04: Medizin: Augenklinik und Poliklinikde_DE
opus.organisation.stringFB 04: Medizin: Institut für Med. Biometrie, Epidemologie und Informatikde_DE
opus.identifier.opusid58658-
opus.institute.number0446-
opus.institute.number0424-
opus.metadataonlyfalse-
opus.type.contenttypeKeinede_DE
opus.type.contenttypeNoneen_GB
opus.affiliatedHopf, Susanne-
opus.affiliatedSchmidtmann, Irene-
opus.affiliatedPitz, Susanne-
jgu.publisher.doi10.1371/journal.pone.0204008
jgu.organisation.rorhttps://ror.org/023b0x485
Appears in collections:JGU-Publikationen

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