Gutenberg Open Science: Spindle bursts in neonatal rat cerebral cortex

Please use this identifier to cite or link to this item: http://doi.org/10.25358/openscience-7570

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DC Field	Value	Language
dc.contributor.author	Yang, Jenq-Wei	-
dc.contributor.author	Reyes-Puerta, Vicente	-
dc.contributor.author	Kilb, Werner	-
dc.contributor.author	Luhmann, Heiko	-
dc.date.accessioned	2022-08-18T10:24:36Z	-
dc.date.available	2022-08-18T10:24:36Z	-
dc.date.issued	2016	-
dc.identifier.uri	https://openscience.ub.uni-mainz.de/handle/20.500.12030/7584	-
dc.description.abstract	Spontaneous and sensory evoked spindle bursts represent a functional hallmark of the developing cerebral cortex in vitro and in vivo. They have been observed in various neocortical areas of numerous species, including newborn rodents and preterm human infants. Spindle bursts are generated in complex neocortical-subcortical circuits involving in many cases the participation of motor brain regions. Together with early gamma oscillations, spindle bursts synchronize the activity of a local neuronal network organized in a cortical column. Disturbances in spindle burst activity during corticogenesis may contribute to disorders in cortical architecture and in the activity-dependent control of programmed cell death. In this review we discuss (i) the functional properties of spindle bursts, (ii) the mechanisms underlying their generation, (iii) the synchronous patterns and cortical networks associated with spindle bursts, and (iv) the physiological and pathophysiological role of spindle bursts during early cortical development.	en_GB
dc.description.sponsorship	DFG, Open Access-Publizieren Universität Mainz / Universitätsmedizin	de
dc.language.iso	eng	de
dc.rights	CC BY	*
dc.rights.uri	https://creativecommons.org/licenses/by/4.0/	*
dc.subject.ddc	610 Medizin	de_DE
dc.subject.ddc	610 Medical sciences	en_GB
dc.title	Spindle bursts in neonatal rat cerebral cortex	en_GB
dc.type	Zeitschriftenaufsatz	de
dc.identifier.doi	http://doi.org/10.25358/openscience-7570	-
jgu.type.dinitype	article	en_GB
jgu.type.version	Published version	de
jgu.type.resource	Text	de
jgu.organisation.department	FB 04 Medizin	de
jgu.organisation.number	2700	-
jgu.organisation.name	Johannes Gutenberg-Universität Mainz	-
jgu.rights.accessrights	openAccess	-
jgu.journal.title	Neural plasticity	de
jgu.journal.volume	2016	de
jgu.pages.alternative	Art. 3467832	de
jgu.publisher.year	2016	-
jgu.publisher.name	Hindawi	de
jgu.publisher.place	New York, NY	de
jgu.publisher.uri	http://dx.doi.org/10.1155/2016/3467832	de
jgu.publisher.issn	1687-5443	de
jgu.publisher.issn	2090-5904	de
jgu.publisher.issn	0792-8483	de
jgu.organisation.place	Mainz	-
jgu.subject.ddccode	610	de
opus.date.modified	2018-08-23T08:20:21Z	-
opus.subject.dfgcode	00-000	-
opus.organisation.string	FB 04: Medizin: Institut für Physiologie und Pathophysiologie	de_DE
opus.identifier.opusid	56317	-
opus.institute.number	0403	-
opus.metadataonly	false	-
opus.type.contenttype	Keine	de_DE
opus.type.contenttype	None	en_EN
opus.affiliated	Reyes-Puerta, Vicente	-
opus.affiliated	Luhmann, Heiko	-
jgu.publisher.doi	10.1155/2016/3467832	de
jgu.organisation.ror	https://ror.org/023b0x485	-
Appears in collections:	DFG-OA-Publizieren (2012 - 2017)

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