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Please use this identifier to cite or link to this item: http://doi.org/10.25358/openscience-7521
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dc.contributor.authorKeller, Karsten-
dc.contributor.authorSinning, Christoph-
dc.contributor.authorSchulz, Andreas-
dc.contributor.authorJünger, Claus-
dc.contributor.authorSchmitt, Volker H.-
dc.contributor.authorHahad, Omar-
dc.contributor.authorZeller, Tanja-
dc.contributor.authorBeutel, Manfred-
dc.contributor.authorPfeiffer, Norbert-
dc.contributor.authorStrauch, Konstantin-
dc.contributor.authorBlankenberg, Stefan-
dc.contributor.authorLackner, Karl J.-
dc.contributor.authorProchaska, Jürgen H.-
dc.contributor.authorSchulz, Eberhard-
dc.contributor.authorMünzel, Thomas-
dc.contributor.authorWild, Philipp S.-
dc.date.accessioned2022-08-05T10:12:05Z-
dc.date.available2022-08-05T10:12:05Z-
dc.date.issued2021-
dc.identifier.urihttps://openscience.ub.uni-mainz.de/handle/20.500.12030/7535-
dc.description.abstractEchocardiography is the most common routine cardiac imaging method. Nevertheless, only few data about sex-specific reference limits for right atrium (RA) dimensions are available. Transthoracic echocardiographic RA measurements were studied in 9511 participants of the Gutenberg-Health-Study. A reference sample of 1942 cardiovascular healthy subjects without chronic obstructive pulmonary disease was defined. We assessed RA dimensions and sex-specific reference limits were defined using the 95th percentile of the reference sample. Results showed sex-specific differences with larger RA dimensions in men that were attenuated by standardization for body-height. RA-volume was 20.2 ml/m in women (5th–95th: 12.7–30.4 ml/m) and 26.1 ml/m in men (5th–95th: 16.0–40.5 ml/m). Multivariable regressions identified body-mass-index (BMI), coronary artery disease (CAD), chronic heart failure (CHF) and atrial fibrillation (AF) as independent key correlates of RA-volume in both sexes. All-cause mortality after median follow-up-period of 10.7 (9.81/11.6) years was higher in individuals who had RA volume/height outside the 95% reference limit (HR 1.70 [95%CI 1.29–2.23], P = 0.00014)). Based on a large community-based sample, we present sex-specific reference-values for RA dimensions normalized for height. RA-volume varies with BMI, CHF, CAD and AF in both sexes. Individuals with RA-volume outside the reference limit had a 1.7-fold higher mortality than those within reference limits.en_GB
dc.language.isoengde
dc.rightsCC BY*
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/*
dc.subject.ddc610 Medizinde_DE
dc.subject.ddc610 Medical sciencesen_GB
dc.titleRight atrium size in the general populationen_GB
dc.typeZeitschriftenaufsatzde
dc.identifier.doihttp://doi.org/10.25358/openscience-7521-
jgu.type.dinitypearticleen_GB
jgu.type.versionPublished versionde
jgu.type.resourceTextde
jgu.organisation.departmentFB 04 Medizinde
jgu.organisation.number2700-
jgu.organisation.nameJohannes Gutenberg-Universität Mainz-
jgu.rights.accessrightsopenAccess-
jgu.journal.titleScientific reportsde
jgu.journal.volume11de
jgu.pages.alternative22523de
jgu.publisher.year2021-
jgu.publisher.nameMacmillan Publishers Limited, part of Springer Naturede
jgu.publisher.placeLondonde
jgu.publisher.issn2045-2322de
jgu.organisation.placeMainz-
jgu.subject.ddccode610de
jgu.publisher.doi10.1038/s41598-021-01968-yde
jgu.organisation.rorhttps://ror.org/023b0x485-
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