Please use this identifier to cite or link to this item: http://doi.org/10.25358/openscience-688
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dc.contributor.authorSchuster, Alexander K.-
dc.contributor.authorFischer, Joachim Ernst-
dc.contributor.authorVossmerbäumer, Urs-
dc.date.accessioned2016-07-21T09:51:53Z-
dc.date.available2016-07-21T11:51:53Z-
dc.date.issued2016-
dc.identifier.urihttps://openscience.ub.uni-mainz.de/handle/20.500.12030/690-
dc.description.abstractBackground. Optical coherence tomography (OCT) allows quantitative analysis of the anterior segment of the eye with a noncontact examination. The aim of this study is to analyze associations of central corneal thickness (CCT) as measured by OCT with ocular and systemic cardiovascular parameters. Methods. A cross-sectional study of 734 persons was performed in a working age population. Only healthy eyes were included. A comprehensive ophthalmological examination including refraction, noncontact tonometry, and imaging of the anterior segment by SD-OCT was performed. In parallel, a broad range of systemic cardiovascular parameters were measured. Associations were analyzed using a generalized estimating equations' model. Results. CCT measurements showed a significant association with corneal curvature and intraocular pressure: a thinner CCT was associated with a flatter cornea and with lower intraocular pressure (p < 0.001). Age was positively associated with CCT (p < 0.001); all other cardiovascular parameters were not associated. Conclusion. A thinner cornea is associated with a flatter surface and with lower intraocular pressure readings, while there are no independent associations with refraction and systemic cardiovascular parameters. Our findings highlight the value of SD-OCT CCT measurements as a standard tool in anterior segment analysis.en_GB
dc.description.sponsorshipDFG, Open Access-Publizieren Universität Mainz / Universitätsmedizin-
dc.language.isoeng-
dc.rightsCC BYde_DE
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/-
dc.subject.ddc610 Medizinde_DE
dc.subject.ddc610 Medical sciencesen_GB
dc.titleCentral corneal thickness in spectral-domain OCT and associations with ocular and systemic parametersen_GB
dc.typeZeitschriftenaufsatzde_DE
dc.identifier.urnurn:nbn:de:hebis:77-publ-544032-
dc.identifier.doihttp://doi.org/10.25358/openscience-688-
jgu.type.dinitypearticle-
jgu.type.versionPublished versionen_GB
jgu.type.resourceText-
jgu.organisation.departmentFB 04 Medizin-
jgu.organisation.number2700-
jgu.organisation.nameJohannes Gutenberg-Universität Mainz-
jgu.rights.accessrightsopenAccess-
jgu.journal.titleJournal of Ophthalmology-
jgu.journal.volume2016-
jgu.pages.alternativeArt. 2596956-
jgu.publisher.year2016-
jgu.publisher.nameHindawi-
jgu.publisher.placeNew York, NY-
jgu.publisher.urihttp://dx.doi.org/10.1155/2016/2596956-
jgu.publisher.issn2090-004X-
jgu.organisation.placeMainz-
jgu.subject.ddccode610-
opus.date.accessioned2016-07-21T09:51:53Z-
opus.date.modified2018-08-23T08:25:12Z-
opus.date.available2016-07-21T11:51:53-
opus.subject.dfgcode04-205-
opus.organisation.stringFB 04: Medizin: Augenklinik und Poliklinikde_DE
opus.identifier.opusid54403-
opus.institute.number0446-
opus.metadataonlyfalse-
opus.type.contenttypeElektronische Ressourcede_DE
opus.type.contenttypeElectronic Resourceen_GB
opus.affiliatedSchuster, Alexander K.-
opus.affiliatedVossmerbäumer, Urs-
jgu.publisher.doi10.1155/2016/2596956
jgu.organisation.rorhttps://ror.org/023b0x485
Appears in collections:JGU-Publikationen

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