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http://doi.org/10.25358/openscience-688
Autoren: | Schuster, Alexander K. Fischer, Joachim Ernst Vossmerbäumer, Urs |
Titel: | Central corneal thickness in spectral-domain OCT and associations with ocular and systemic parameters |
Online-Publikationsdatum: | 21-Jul-2016 |
Erscheinungsdatum: | 2016 |
Sprache des Dokuments: | Englisch |
Zusammenfassung/Abstract: | Background. Optical coherence tomography (OCT) allows quantitative analysis of the anterior segment of the eye with a noncontact examination. The aim of this study is to analyze associations of central corneal thickness (CCT) as measured by OCT with ocular and systemic cardiovascular parameters. Methods. A cross-sectional study of 734 persons was performed in a working age population. Only healthy eyes were included. A comprehensive ophthalmological examination including refraction, noncontact tonometry, and imaging of the anterior segment by SD-OCT was performed. In parallel, a broad range of systemic cardiovascular parameters were measured. Associations were analyzed using a generalized estimating equations' model. Results. CCT measurements showed a significant association with corneal curvature and intraocular pressure: a thinner CCT was associated with a flatter cornea and with lower intraocular pressure (p < 0.001). Age was positively associated with CCT (p < 0.001); all other cardiovascular parameters were not associated. Conclusion. A thinner cornea is associated with a flatter surface and with lower intraocular pressure readings, while there are no independent associations with refraction and systemic cardiovascular parameters. Our findings highlight the value of SD-OCT CCT measurements as a standard tool in anterior segment analysis. |
DDC-Sachgruppe: | 610 Medizin 610 Medical sciences |
Veröffentlichende Institution: | Johannes Gutenberg-Universität Mainz |
Organisationseinheit: | FB 04 Medizin |
Veröffentlichungsort: | Mainz |
ROR: | https://ror.org/023b0x485 |
DOI: | http://doi.org/10.25358/openscience-688 |
URN: | urn:nbn:de:hebis:77-publ-544032 |
Version: | Published version |
Publikationstyp: | Zeitschriftenaufsatz |
Nutzungsrechte: | CC BY |
Informationen zu den Nutzungsrechten: | https://creativecommons.org/licenses/by/4.0/ |
Zeitschrift: | Journal of Ophthalmology 2016 |
Seitenzahl oder Artikelnummer: | Art. 2596956 |
Verlag: | Hindawi |
Verlagsort: | New York, NY |
Erscheinungsdatum: | 2016 |
ISSN: | 2090-004X |
URL der Originalveröffentlichung: | http://dx.doi.org/10.1155/2016/2596956 |
DOI der Originalveröffentlichung: | 10.1155/2016/2596956 |
Enthalten in den Sammlungen: | JGU-Publikationen |
Dateien zu dieser Ressource:
Datei | Beschreibung | Größe | Format | ||
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54403.pdf | 619.87 kB | Adobe PDF | Öffnen/Anzeigen |