Gutenberg Open Science: Xylochemical synthesis and biological evaluation of shancigusin C and bletistrin G ‡

Please use this identifier to cite or link to this item: http://doi.org/10.25358/openscience-6508

Full metadata record

DC Field	Value	Language
dc.contributor.author	Geske, Leander	-
dc.contributor.author	Kauhl, Ulrich	-
dc.contributor.author	Saaed, Mohamed E. M.	-
dc.contributor.author	Schüffler, Anja	-
dc.contributor.author	Thines, Eckhard	-
dc.contributor.author	Efferth, Thomas	-
dc.contributor.author	Opatz, Till	-
dc.date.accessioned	2021-11-15T10:12:53Z	-
dc.date.available	2021-11-15T10:12:53Z	-
dc.date.issued	2021	-
dc.identifier.uri	https://openscience.ub.uni-mainz.de/handle/20.500.12030/6518	-
dc.description.abstract	The biological activities of shancigusin C (1) and bletistrin G (2), natural products isolated from orchids, are reported along with their first total syntheses. The total synthesis of shancigusin C (1) was conducted by employing the Perkin reaction to forge the central stilbene core, whereas the synthesis of bletistrin G (2) was achieved by the Wittig olefination followed by several regioselective aromatic substitution reactions. Both syntheses were completed by applying only renewable starting materials according to the principles of xylochemistry. The cytotoxic properties of shancigusin C (1) and bletistrin G (2) against tumor cells suggest suitability as a starting point for further structural variation.	en_GB
dc.description.sponsorship	Open Access-Publizieren Universität Mainz / Universitätsmedizin Mainz	de
dc.language.iso	eng	de
dc.rights	CC BY	*
dc.rights.uri	https://creativecommons.org/licenses/by/4.0/	*
dc.subject.ddc	570 Biowissenschaften	de_DE
dc.subject.ddc	570 Life sciences	en_GB
dc.title	Xylochemical synthesis and biological evaluation of shancigusin C and bletistrin G ‡	en_GB
dc.type	Zeitschriftenaufsatz	de
dc.identifier.doi	http://doi.org/10.25358/openscience-6508	-
jgu.type.dinitype	article	en_GB
jgu.type.version	Published version	de
jgu.type.resource	Text	de
jgu.organisation.department	FB 09 Chemie, Pharmazie u. Geowissensch.	de
jgu.organisation.number	7950	-
jgu.organisation.name	Johannes Gutenberg-Universität Mainz	-
jgu.rights.accessrights	openAccess	-
jgu.journal.title	Molecules	de
jgu.journal.volume	26	de
jgu.journal.issue	11	de
jgu.pages.alternative	3224	de
jgu.publisher.year	2021	-
jgu.publisher.name	MDPI	de
jgu.publisher.place	Basel	de
jgu.publisher.uri	https://doi.org/10.3390/molecules26113224	de
jgu.publisher.issn	1420-3049	de
jgu.organisation.place	Mainz	-
jgu.publisher.doi	10.3390/molecules26113224
jgu.organisation.ror	https://ror.org/023b0x485
Appears in collections:	JGU-Publikationen

Files in This Item:

	File	Description	Size	Format
	geske_leander-xylochemical_s-20211115110748732.pdf		3.37 MB	Adobe PDF	View/Open

Show simple item record