Please use this identifier to cite or link to this item: http://doi.org/10.25358/openscience-257
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dc.contributor.authorWasielica-Poslednik, Joanna-
dc.contributor.authorGericke, Adrian-
dc.contributor.authorDesuki, Alexander-
dc.contributor.authorSchlötzer-Schrehardt, Ursula-
dc.contributor.authorPfeiffer, Norbert-
dc.contributor.authorLisch, Walter-
dc.date.accessioned2018-12-19T13:20:27Z-
dc.date.available2018-12-19T14:20:27Z-
dc.date.issued2018-
dc.identifier.urihttps://openscience.ub.uni-mainz.de/handle/20.500.12030/259-
dc.description.abstractPurpose To report on a case of recurrence of paraproteinemic keratopathy (PPK) associated with monoclonal gammopathy after bilateral penetrating keratoplasty. Observations Penetrating keratoplasty was performed on both eyes of a 45-year-old man due to bilateral progressive corneal stromal clouding. Recurrence of the corneal stromal opacities accompanied by a decrease in visual acuity was observed on slit-lamp examination already two years after penetrating keratoplasty. Confocal laser scanning microscopy (CLSM) of the corneal grafts performed three years after penetrating keratoplasty showed bilateral morphological changes identical to that found in the patient's corneas prior to penetrating keratoplasty. A hematological work-up revealed monoclonal gammopathy of type IgG kappa. The histochemical examination of the explanted corneas confirmed the diagnosis of PPK. Conclusions and importance Paraproteinemic keratopathy is an underdiagnosed ophthalmological condition, which may be associated with potentially life-threatening hematologic disorders. A hematological workup should be performed in patients with corneal opacities of uncertain etiology. Penetrating keratoplasty should be performed with caution in patients with monoclonal gammopathy due to the possibility of a very fast recurrence of PPK in the corneal graft. This is the first presentation of the recurrence of flake like PPK after penetrating keratoplasty assessed with CLSM.en_GB
dc.description.sponsorshipDFG, Open Access-Publizieren Universität Mainz / Universitätsmedizin-
dc.language.isoeng-
dc.rightsCC BY-NC-NDde_DE
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/-
dc.subject.ddc610 Medizinde_DE
dc.subject.ddc610 Medical sciencesen_GB
dc.titleRecurrence of paraproteinemic keratopathy after penetrating keratoplasty and its assessment with confocal microscopyen_GB
dc.typeZeitschriftenaufsatzde_DE
dc.identifier.urnurn:nbn:de:hebis:77-publ-587133-
dc.identifier.doihttp://doi.org/10.25358/openscience-257-
jgu.type.dinitypearticle-
jgu.type.versionPublished versionen_GB
jgu.type.resourceText-
jgu.organisation.departmentFB 04 Medizin-
jgu.organisation.number2700-
jgu.organisation.nameJohannes Gutenberg-Universität Mainz-
jgu.rights.accessrightsopenAccess-
jgu.journal.titleAmerican journal of ophthalmology : Case reports-
jgu.journal.volume11-
jgu.pages.start87-
jgu.pages.end91-
jgu.publisher.year2018-
jgu.publisher.nameElsevier-
jgu.publisher.placeAmsterdam-
jgu.publisher.urihttp://dx.doi.org/10.1016/j.ajoc.2018.06.014-
jgu.publisher.issn2451-9936-
jgu.organisation.placeMainz-
jgu.subject.ddccode610-
opus.date.accessioned2018-12-19T13:20:27Z-
opus.date.modified2019-01-16T09:12:30Z-
opus.date.available2018-12-19T14:20:27-
opus.subject.dfgcode00-000-
opus.organisation.stringFB 04: Medizin: III. Medizinische Klinik und Poliklinikde_DE
opus.organisation.stringFB 04: Medizin: Augenklinik und Poliklinikde_DE
opus.identifier.opusid58713-
opus.institute.number0427-
opus.institute.number0446-
opus.metadataonlyfalse-
opus.type.contenttypeKeinede_DE
opus.type.contenttypeNoneen_GB
opus.affiliatedWasielica-Poslednik, Joanna-
opus.affiliatedGericke, Adrian-
opus.affiliatedPfeiffer, Norbert-
jgu.publisher.doi10.1016/j.ajoc.2018.06.014
jgu.organisation.rorhttps://ror.org/023b0x485
Appears in collections:JGU-Publikationen

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