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PreviewIssue dateOnline publication dateTitleAuthor(s)
3261.pdf.jpg201231-Jan-2013Shikonin directly targets mitochondria and causes mitochondrial dysfunction in cancer cellsWiench, Benjamin; Eichhorn, Tolga; Paulsen, Malte; Efferth, Thomas
dawood_mona-collateral_sen-20200928110332836.pdf.jpg201913-Jun-2019Collateral sensitivity of parthenolide via NF-κB and HIF-α inhibition and epigenetic changes in drug-resistant cancer cell linesDawood, Mona; Ooko, Edna; Efferth, Thomas
özenver_nadire-chemometric_an-20210209112718237.pdf.jpg20209-Feb-2021Chemometric and transcriptomic profiling, microtubule disruption and cell death induction by secalonic acid in tumor cellsÖzenver, Nadire; Dawood, Mona; Fleischer, Edmond; Klinger, Anette; Efferth, Thomas
kadioglu_onat-identification-20210209101413928.pdf.jpg20209-Feb-2021Identification of novel rare ABCC1 transporter mutations in tumor biopsies of cancer patientsKadioglu, Onat; Saeed, Mohamed; Munder, Markus; Spuller, Andreas; Greten, Henry Johannes; Efferth, Thomas
saeed_mohamed_e._m.-drug_repurposi-20210510114527807.pdf.jpg202110-May-2021Drug repurposing using transcriptome sequencing and virtual drug screening in a patient with glioblastomaSaeed, Mohamed E. M.; Kadioglu, Onat; Greten, Henry Johannes; Yildirim, Adem; Mayr, Katharina; Wenz, Frederik; Giordano, Frank; Efferth, Thomas
selection_of_safe_artemisinin-20220624130755185.pdf.jpg202127-Jun-2022Selection of safe artemisinin derivatives using a machine learning-based cardiotoxicity platform and in vitro and in vivo validationKadioglu, Onat; Klauck, Sabine M.; Fleischer, Edmond; Shan, Letian; Efferth, Thomas
geske_leander-xylochemical_s-20211115110748732.pdf.jpg202115-Nov-2021Xylochemical synthesis and biological evaluation of shancigusin C and bletistrin G ‡Geske, Leander; Kauhl, Ulrich; Saaed, Mohamed E. M.; Schüffler, Anja; Thines, Eckhard; Efferth, Thomas; Opatz, Till
network_pharmacology_of_tript-20220729131545075.pdf.jpg20213-Aug-2022Network pharmacology of triptolide in cancer cells : implications for transcription factor bindingSeo, Ean-Jeong; Dawood, Mona; Hult, Annika K.; Olsson, Martin L.; Efferth, Thomas
pyrrolizidine_alkaloids_cause-20220701131337232.pdf.jpg20224-Jul-2022Pyrrolizidine alkaloids cause cell cycle and DNA damage repair defects as analyzed by transcriptomics in cytochrome P450 3A4-overexpressing HepG2 clone 9 cellsAbdelfatah, Sara; Naß, Janine; Knorz, Caroline; Klauck, Sabine M.; Küpper, Jan-Heiner; Efferth, Thomas
identification_of_potential_n-20220701123610800.pdf.jpg20214-Jul-2022Identification of potential novel drug resistance mechanisms by genomic and transcriptomic profiling of colon cancer cells with p53 deletionKadioglu, Onat; Saeed, Mohamed; Mahmoud, Nuha; Azawi, Shaymaa; Mrasek, Kristin; Liehr, Thomas; Efferth, Thomas