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Results 1-10 of 13 (Search time: 0.008 seconds).
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PreviewIssue dateOnline publication dateTitleAuthor(s)
3261.pdf.jpg201231-Jan-2013Shikonin directly targets mitochondria and causes mitochondrial dysfunction in cancer cellsWiench, Benjamin; Eichhorn, Tolga; Paulsen, Malte; Efferth, Thomas
identification_of_potential_n-20220701123610800.pdf.jpg20214-Jul-2022Identification of potential novel drug resistance mechanisms by genomic and transcriptomic profiling of colon cancer cells with p53 deletionKadioglu, Onat; Saeed, Mohamed; Mahmoud, Nuha; Azawi, Shaymaa; Mrasek, Kristin; Liehr, Thomas; Efferth, Thomas
a_novel_ligand_of_the_transla-20220701124103992.pdf.jpg20214-Jul-2022A novel ligand of the translationally controlled tumor protein (TCTP) identified by virtual drug screening for cancer differentiation therapyFischer, Nicolas; Seo, Ean-Jeong; Abdelfatah, Sara; Fleischer, Edmond; Klinger, Anette; Efferth, Thomas
pyrrolizidine_alkaloids_cause-20220701131337232.pdf.jpg20224-Jul-2022Pyrrolizidine alkaloids cause cell cycle and DNA damage repair defects as analyzed by transcriptomics in cytochrome P450 3A4-overexpressing HepG2 clone 9 cellsAbdelfatah, Sara; Naß, Janine; Knorz, Caroline; Klauck, Sabine M.; Küpper, Jan-Heiner; Efferth, Thomas
selection_of_safe_artemisinin-20220624130755185.pdf.jpg202127-Jun-2022Selection of safe artemisinin derivatives using a machine learning-based cardiotoxicity platform and in vitro and in vivo validationKadioglu, Onat; Klauck, Sabine M.; Fleischer, Edmond; Shan, Letian; Efferth, Thomas
network_pharmacology_of_tript-20220729131545075.pdf.jpg20213-Aug-2022Network pharmacology of triptolide in cancer cells : implications for transcription factor bindingSeo, Ean-Jeong; Dawood, Mona; Hult, Annika K.; Olsson, Martin L.; Efferth, Thomas
small_molecules_targeting_apo-20231004235309084.pdf.jpg202317-Oct-2023Small molecules targeting apoptosis and parthanatos in sensitive and drug-resistant tumor cellsEfferth, Thomas; Zhou, Min
dawood_mona-collateral_sen-20200928110332836.pdf.jpg201913-Jun-2019Collateral sensitivity of parthenolide via NF-κB and HIF-α inhibition and epigenetic changes in drug-resistant cancer cell linesDawood, Mona; Ooko, Edna; Efferth, Thomas
geske_leander-xylochemical_s-20211115110748732.pdf.jpg202115-Nov-2021Xylochemical synthesis and biological evaluation of shancigusin C and bletistrin G ‡Geske, Leander; Kauhl, Ulrich; Saaed, Mohamed E. M.; Schüffler, Anja; Thines, Eckhard; Efferth, Thomas; Opatz, Till
özenver_nadire-chemometric_an-20210209112718237.pdf.jpg20209-Feb-2021Chemometric and transcriptomic profiling, microtubule disruption and cell death induction by secalonic acid in tumor cellsÖzenver, Nadire; Dawood, Mona; Fleischer, Edmond; Klinger, Anette; Efferth, Thomas

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