Please use this identifier to cite or link to this item: http://doi.org/10.25358/openscience-183
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dc.contributor.authorPolimeni, Alberto-
dc.contributor.authorAnadol, Remzi-
dc.contributor.authorMünzel, Thomas-
dc.contributor.authorGeyer, Martin-
dc.contributor.authorDe Rosa, Salvatore-
dc.contributor.authorIndolfi, Ciro-
dc.contributor.authorGori, Tommaso-
dc.date.accessioned2019-07-11T06:42:44Z-
dc.date.available2019-07-11T08:42:44Z-
dc.date.issued2019-
dc.identifier.urihttps://openscience.ub.uni-mainz.de/handle/20.500.12030/185-
dc.description.abstractBackground: BRS represent a new approach to treating coronary artery disease. Beneficial properties of BRS regardingthe restoration of vasomotility after resorption make themattractive devices in CTO revascularization. However,experience in this setting is limited. Methods: We systematically searched Medline, Scholar, and Scopus for reports of at least 9 patients with CTOundergoing BRS implantation. Patients’and procedural characteristics weresummarized. The primary outcome ofinterest was target lesion revascularization (TLR). Pooled estimates were calculated using a random-effectsmeta-analysis. The study protocol was registered in PROSPERO (CRD42017069322). Results: Thirteen reports for a total of 843 lesions with a median follow-up of 12 months (IQR 6–12) wereincluded in the analysis. At short-term, the summary estimate rate of TLR was 2.6% (95% CI: 1 to 4%, I2=0%,P=0.887)while at mid to long-term it was 3.8% (95% CI: 2 to 6%, I2=0%,P= 0.803). At long-term follow-up (≥12 months), thesummary estimate rate of cardiac death was 1.1% (95% CI: 0 to 2%, I2= 0%, P = 0.887). The summary estimate rates ofscaffold thrombosis and clinical restenosis were respectively 0.9% (95% CI: 0 to 2%, I2=0%,P= 0.919) and 1.8% (95% CI:0to4%,I2=0%,P= 0.448). Finally, the summary estimate rate of target vessel revascularization was 6.6% (95% CI: 0 to11%, I2=0%,P=0.04). Conclusions: Implantation of BRS in a population with CTO is feasible, although further longer-term outcome studiesare necessary.en_GB
dc.description.sponsorshipDFG, Open Access-Publizieren Universität Mainz / Universitätsmedizin-
dc.language.isoeng-
dc.rightsCC BYde_DE
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/-
dc.subject.ddc610 Medizinde_DE
dc.subject.ddc610 Medical sciencesen_GB
dc.titleBioresorbable vascular scaffolds for percutaneous treatment of chronic total coronary occlusions occlusions : a meta-analysisen_GB
dc.typeZeitschriftenaufsatzde_DE
dc.identifier.doihttp://doi.org/10.25358/openscience-183-
jgu.type.dinitypearticle-
jgu.type.versionPublished versionen_GB
jgu.type.resourceText-
jgu.organisation.departmentFB 04 Medizin-
jgu.organisation.number2700-
jgu.organisation.nameJohannes Gutenberg-Universität Mainz-
jgu.rights.accessrightsopenAccess-
jgu.journal.titleBMC cardiovascular disorders-
jgu.journal.volume19-
jgu.pages.alternativeArt. 59-
jgu.publisher.year2019-
jgu.publisher.nameBioMed Central-
jgu.publisher.placeLondon-
jgu.publisher.urihttp://dx.doi.org/10.1186/s12872-019-1042-2-
jgu.publisher.issn1471-2261-
jgu.organisation.placeMainz-
jgu.subject.ddccode610-
opus.date.accessioned2019-07-11T06:42:44Z-
opus.date.modified2019-08-07T09:08:03Z-
opus.date.available2019-07-11T08:42:44-
opus.subject.dfgcode00-000-
opus.organisation.stringFB 04: Medizin: Kardiologie Ide_DE
opus.identifier.opusid59152-
opus.institute.number0467-
opus.metadataonlyfalse-
opus.type.contenttypeKeinede_DE
opus.type.contenttypeNoneen_GB
opus.affiliatedMünzel, Thomas-
opus.affiliatedGeyer, Martin-
opus.affiliatedGori, Tommaso-
jgu.publisher.doi10.1186/s12872-019-1042-2
jgu.organisation.rorhttps://ror.org/023b0x485
Appears in collections:JGU-Publikationen

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