Please use this identifier to cite or link to this item:
http://doi.org/10.25358/openscience-168Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Boeder, Niklas F. | - |
| dc.contributor.author | Weissner, Melissa | - |
| dc.contributor.author | Blachutzik, Florian | - |
| dc.contributor.author | Ullrich, Helen | - |
| dc.contributor.author | Anadol, Remzi | - |
| dc.contributor.author | Tröbs, Monique | - |
| dc.contributor.author | Münzel, Thomas | - |
| dc.contributor.author | Hamm, Christian W. | - |
| dc.contributor.author | Dijkstra, Jouke | - |
| dc.contributor.author | Achenbach, Stephan | - |
| dc.contributor.author | Nef, Holger M. | - |
| dc.contributor.author | Gori, Tommaso | - |
| dc.date.accessioned | 2019-07-08T11:32:39Z | - |
| dc.date.available | 2019-07-08T13:32:39Z | - |
| dc.date.issued | 2019 | - |
| dc.identifier.uri | https://openscience.ub.uni-mainz.de/handle/20.500.12030/170 | - |
| dc.description.abstract | Malapposition is a common finding in stent and scaffold thrombosis (ScT). Evidence from studies with prospective follow-up, however, is scarce. We hypothesized that incidental observations of strut malapposition might be predictive of late ScT during subsequent follow-up. One hundred ninety-seven patients were enrolled in a multicentre registry with prospective follow-up. Optical coherence tomography (OCT), performed in an elective setting, was available in all at 353 (0–376) days after bioresorbable scaffold (BRS) implantation. Forty-four patients showed evidence of malapposition that was deemed not worthy of intervention. Malapposition was not associated with any clinical or procedural parameter except for a higher implantation pressure (p = 0.0008). OCT revealed that malapposition was associated with larger vessel size, less eccentricity (all p < 0.01), and a tendency for more uncovered struts (p = 0.06). Late or very late ScT was recorded in seven of these patients 293 (38–579) days after OCT. OCT-diagnosed malapposition was a predictor of late and very late scaffold thrombosis (p < 0.001) that was independent of the timing of diagnosis. We provide evidence that an incidental finding of malapposition—regardless of the timing of diagnosis of the malapposition—during an elective exam is a predictor of late and very late ScT. Our data provide a rationale to consider prolonged dual antiplatelet therapy if strut malapposition is observed. | en_GB |
| dc.description.sponsorship | DFG, Open Access-Publizieren Universität Mainz / Universitätsmedizin | - |
| dc.language.iso | eng | - |
| dc.rights | CC BY | de_DE |
| dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | - |
| dc.subject.ddc | 610 Medizin | de_DE |
| dc.subject.ddc | 610 Medical sciences | en_GB |
| dc.title | Incidental finding of strut malapposition is a predictor of late and very late thrombosis in coronary bioresorbable scaffolds | en_GB |
| dc.type | Zeitschriftenaufsatz | de_DE |
| dc.identifier.urn | urn:nbn:de:hebis:77-publ-591366 | - |
| dc.identifier.doi | http://doi.org/10.25358/openscience-168 | - |
| jgu.type.dinitype | article | - |
| jgu.type.version | Published version | en_GB |
| jgu.type.resource | Text | - |
| jgu.organisation.department | FB 04 Medizin | - |
| jgu.organisation.number | 2700 | - |
| jgu.organisation.name | Johannes Gutenberg-Universität Mainz | - |
| jgu.rights.accessrights | openAccess | - |
| jgu.journal.title | Journal of Clinical Medicine | - |
| jgu.journal.volume | 8 | - |
| jgu.journal.issue | 5 | - |
| jgu.pages.alternative | Art. 580 | - |
| jgu.publisher.year | 2019 | - |
| jgu.publisher.name | MDPI | - |
| jgu.publisher.place | Basel | - |
| jgu.publisher.uri | http://dx.doi.org/10.3390/jcm8050580 | - |
| jgu.publisher.issn | 2077-0383 | - |
| jgu.organisation.place | Mainz | - |
| jgu.subject.ddccode | 610 | - |
| opus.date.accessioned | 2019-07-08T11:32:39Z | - |
| opus.date.modified | 2020-03-16T11:29:38Z | - |
| opus.date.available | 2019-07-08T13:32:39 | - |
| opus.subject.dfgcode | 00-000 | - |
| opus.organisation.string | FB 04: Medizin: Zentrum für Kardiologie | de_DE |
| opus.identifier.opusid | 59136 | - |
| opus.institute.number | 0466 | - |
| opus.metadataonly | false | - |
| opus.type.contenttype | Keine | de_DE |
| opus.type.contenttype | None | en_GB |
| opus.affiliated | Münzel, Thomas | - |
| jgu.publisher.doi | 10.3390/jcm8050580 | |
| jgu.organisation.ror | https://ror.org/023b0x485 | |
| Appears in collections: | JGU-Publikationen | |
