Please use this identifier to cite or link to this item:
http://doi.org/10.25358/openscience-159Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Negroni, Matteo | - |
| dc.contributor.author | Foitzik, Susanne | - |
| dc.contributor.author | Feldmeyer, Barbara | - |
| dc.date.accessioned | 2019-07-08T08:24:35Z | - |
| dc.date.available | 2019-07-08T10:24:35Z | - |
| dc.date.issued | 2019 | - |
| dc.identifier.uri | https://openscience.ub.uni-mainz.de/handle/20.500.12030/161 | - |
| dc.description.abstract | Senescence is manifested by an increase in molecular damage and a deterioration of biological functions with age. In most organisms, body maintenance is traded-off with reproduction. This negative relationship between longevity and fecundity is also evident on the molecular level. Exempt from this negative trait association, social insect queens are both extremely long-lived and highly fecund. Here, we study changes in gene expression with age and fecundity in ant queens to understand the molecular basis of their long lifespan. We analyse tissue-specific gene expression in young founding queens and old fecund queens of the ant Temnothorax rugatulus. More genes altered their expression with age in the fat body than in the brain. Despite strong differences in ovary development, few fecundity genes were differentially expressed. Young founding queens invested in immunity (i.e. activation of Toll signalling pathway) and resistance against environmental and physiological stress (i.e. down-regulation of TOR pathway). Conversely, established older queens invested into anti-aging mechanisms through an overproduction of antioxidants (i.e. upregulation of catalase, superoxide dismutase). Finally, we identified candidate genes and pathways, potentially involved in the association between fertility and longevity in social insects and its proximate basis. | en_GB |
| dc.description.sponsorship | DFG, Open Access-Publizieren Universität Mainz / Universitätsmedizin | - |
| dc.language.iso | eng | - |
| dc.rights | CC BY | de_DE |
| dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | - |
| dc.subject.ddc | 570 Biowissenschaften | de_DE |
| dc.subject.ddc | 570 Life sciences | en_GB |
| dc.title | Long-lived Temnothorax ant queens switch from investment in immunity to antioxidant production with age | en_GB |
| dc.type | Zeitschriftenaufsatz | de_DE |
| dc.identifier.urn | urn:nbn:de:hebis:77-publ-591273 | - |
| dc.identifier.doi | http://doi.org/10.25358/openscience-159 | - |
| jgu.type.dinitype | article | - |
| jgu.type.version | Published version | en_GB |
| jgu.type.resource | Text | - |
| jgu.organisation.department | FB 10 Biologie | - |
| jgu.organisation.number | 7970 | - |
| jgu.organisation.name | Johannes Gutenberg-Universität Mainz | - |
| jgu.rights.accessrights | openAccess | - |
| jgu.journal.title | Scientific reports | - |
| jgu.journal.volume | 9 | - |
| jgu.pages.alternative | Art. 7270 | - |
| jgu.publisher.year | 2019 | - |
| jgu.publisher.name | Macmillan Publishers Limited, part of Springer Nature | - |
| jgu.publisher.place | London | - |
| jgu.publisher.uri | http://dx.doi.org/10.1038/s41598-019-43796-1 | - |
| jgu.publisher.issn | 2045-2322 | - |
| jgu.organisation.place | Mainz | - |
| jgu.subject.ddccode | 570 | - |
| opus.date.accessioned | 2019-07-08T08:24:35Z | - |
| opus.date.modified | 2019-08-28T09:07:06Z | - |
| opus.date.available | 2019-07-08T10:24:35 | - |
| opus.subject.dfgcode | 00-000 | - |
| opus.organisation.string | FB 10: Biologie: Institut für Organismische und Molekulare Evolutionsbiologie | de_DE |
| opus.identifier.opusid | 59127 | - |
| opus.institute.number | 1011 | - |
| opus.metadataonly | false | - |
| opus.type.contenttype | Keine | de_DE |
| opus.type.contenttype | None | en_GB |
| opus.affiliated | Negroni, Matteo | - |
| opus.affiliated | Foitzik, Susanne | - |
| jgu.publisher.doi | 10.1038/s41598-019-43796-1 | |
| jgu.organisation.ror | https://ror.org/023b0x485 | |
| Appears in collections: | JGU-Publikationen | |
