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Browsing by Author Efferth, Thomas
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Showing results 1 to 20 of 23
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2023
24-Aug-2023
The cardiac glycoside ZINC253504760 induces parthanatos-type cell death and G2/M arrest via downregulation of MEK1/2 phosphorylation in leukemia cells
Zhou, Min
;
Boulos, Joelle C.
;
Klauck, Sabine M.
;
Efferth, Thomas
2020
9-Feb-2021
Chemometric and transcriptomic profiling, microtubule disruption and cell death induction by secalonic acid in tumor cells
Özenver, Nadire
;
Dawood, Mona
;
Fleischer, Edmond
;
Klinger, Anette
;
Efferth, Thomas
2019
13-Jun-2019
Collateral sensitivity of parthenolide via NF-κB and HIF-α inhibition and epigenetic changes in drug-resistant cancer cell lines
Dawood, Mona
;
Ooko, Edna
;
Efferth, Thomas
2023
24-Aug-2023
Cynaropicrin disrupts tubulin and c-Myc-related signaling and induces parthanatos-type cell death in multiple myeloma
Boulos, Joelle C.
;
Omer, Ejlal A.
;
Rigano, Daniela
;
Formisano, Carmen
;
Chatterjee, Manik
;
Leich, Ellen
;
Klauck, Sabine M.
;
Shan, Le-tian
;
Efferth, Thomas
2013
6-Oct-2022
Cytotoxicity and modes of action of the methanol extracts of six Cameroonian medicinal plants against multidrug-resistant tumor cells
Kuete, Victor
;
Fankam, Aimé G.
;
Wiench, Benjamin
;
Efferth, Thomas
2017
21-Oct-2022
Cytotoxicity of endoperoxides from the Caribbean sponge Plakortis halichondrioides towards sensitive and multidrug-resistant leukemia cells : acids vs. esters activity evaluation
Schirmeister, Tanja
;
Oli, Swarna
;
Wu, Hongmei
;
Della Sala, Gerardo
;
Costantino, Valeria
;
Seo, Ean-Jeong
;
Efferth, Thomas
2015
17-Oct-2022
Cytotoxicity of the sesquiterpene lactones neoambrosin and damsin from ambrosia maritima against multidrug-resistant cancer cells
Saaed, Mohamed
;
Jacob, Stefan
;
Sandjo, Louis P.
;
Sugimoto, Yoshikazu
;
Khalid, Hassan E.
;
Opatz, Till
;
Thines, Eckhard
;
Efferth, Thomas
2021
10-May-2021
Drug repurposing using transcriptome sequencing and virtual drug screening in a patient with glioblastoma
Saeed, Mohamed E. M.
;
Kadioglu, Onat
;
Greten, Henry Johannes
;
Yildirim, Adem
;
Mayr, Katharina
;
Wenz, Frederik
;
Giordano, Frank
;
Efferth, Thomas
2020
9-Feb-2021
Identification of novel rare ABCC1 transporter mutations in tumor biopsies of cancer patients
Kadioglu, Onat
;
Saeed, Mohamed
;
Munder, Markus
;
Spuller, Andreas
;
Greten, Henry Johannes
;
Efferth, Thomas
2021
4-Jul-2022
Identification of potential novel drug resistance mechanisms by genomic and transcriptomic profiling of colon cancer cells with p53 deletion
Kadioglu, Onat
;
Saeed, Mohamed
;
Mahmoud, Nuha
;
Azawi, Shaymaa
;
Mrasek, Kristin
;
Liehr, Thomas
;
Efferth, Thomas
2021
9-Nov-2022
The immunosuppressive activity of artemisinin-type drugs towards inflammatory and autoimmune diseases
Efferth, Thomas
;
Oesch, Franz
2016
7-Oct-2022
Interaction of antihistaminic drugs with human translationally controlled tumor protein (TCTP) as novel approach for differentiation therapy
Seo, Ean-Jeong
;
Efferth, Thomas
2021
3-Aug-2022
Network pharmacology of triptolide in cancer cells : implications for transcription factor binding
Seo, Ean-Jeong
;
Dawood, Mona
;
Hult, Annika K.
;
Olsson, Martin L.
;
Efferth, Thomas
2021
4-Jul-2022
A novel ligand of the translationally controlled tumor protein (TCTP) identified by virtual drug screening for cancer differentiation therapy
Fischer, Nicolas
;
Seo, Ean-Jeong
;
Abdelfatah, Sara
;
Fleischer, Edmond
;
Klinger, Anette
;
Efferth, Thomas
2015
14-Sep-2022
Prediction of cancer drug resistance and implications for personalized medicine
Volm, Manfred
;
Efferth, Thomas
2022
4-Jul-2022
Pyrrolizidine alkaloids cause cell cycle and DNA damage repair defects as analyzed by transcriptomics in cytochrome P450 3A4-overexpressing HepG2 clone 9 cells
Abdelfatah, Sara
;
Naß, Janine
;
Knorz, Caroline
;
Klauck, Sabine M.
;
Küpper, Jan-Heiner
;
Efferth, Thomas
2021
27-Jun-2022
Selection of safe artemisinin derivatives using a machine learning-based cardiotoxicity platform and in vitro and in vivo validation
Kadioglu, Onat
;
Klauck, Sabine M.
;
Fleischer, Edmond
;
Shan, Letian
;
Efferth, Thomas
2012
31-Jan-2013
Shikonin directly targets mitochondria and causes mitochondrial dysfunction in cancer cells
Wiench, Benjamin
;
Eichhorn, Tolga
;
Paulsen, Malte
;
Efferth, Thomas
2022
20-Dec-2022
Shikonin inhibits cell growth of sunitinib-resistant renal cell carcinoma by activating the necrosome complex and inhibiting the AKT/mTOR signaling pathway
Markowitsch, Sascha D.
;
Vakhrusheva, Olesya
;
Schupp, Patricia
;
Akele, Yasminn
;
Kitanovic, Jovana
;
Slade, Kimberly S.
;
Efferth, Thomas
;
Thomas, Anita
;
Tsaur, Igor
;
Mager, René
;
Haferkamp, Axel
;
Jüngel, Eva
2021
31-May-2021
Shikonin reduces growth of docetaxel-resistant prostate cancer cells mainly through necroptosis
Markowitsch, Sascha D.
;
Juetter, Kira M.
;
Schupp, Patricia
;
Hauschulte, Kristine
;
Vakhrusheva, Olesya
;
Slade, Kimberly Sue
;
Thomas, Anita
;
Tsaur, Igor
;
Cinatl, Jindrich
;
Michaelis, Martin
;
Efferth, Thomas
;
Haferkamp, Axel
;
Juengel, Eva